29 - Spontaneous Coronary Artery Dissection Flashcards Preview

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Flashcards in 29 - Spontaneous Coronary Artery Dissection Deck (18)
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What is spontaneous coronary artery dissection?

Separation of the coronary artery media by hemorrhage with or without an associated intimal teat and isn't associated with aortic root dissection nor is it a consequence of coronary angioplasty or angiography, cardiac surgery or chest trauma


What demographic is most commonly affected by SCAD?

- Occurs most often in young women (age


Which coronary artery is the most frequently involved vessel?

Left anterior descending coronary artery (LAD)


What percent of cases present with multi-vessel dissection?



What is the original presentation of these patients?

- Acute coronary syndrome (ACS)
- Sudden cardiac death (they just die from this)


What is ESSENTIAL in the diagnosis of SCAD?


Early CORONARY ANGIOGRAPHY remains essential in the diagnosis


What other types of imaging provide detailed information on the location and extent of the dissection?

- IVUS (Intravascular ultrasound)
- OCT (Optical coherence tomography)


Describe the treatment of SCAD patients with ongoing myocardial ischemia

Pts w/ ongoing myocardial ischemia must be treated with early revascularization (PCI or CABG)


Describe the treatment of SCAD patients with limited flow

Pts w/o flow limiting dissection should be treated conservatively as spontaneous healing is possible


Do patients with SCAD typically have a high risk profile for coronary artery disease?

No - typically a low coronary risk profile

Not your typical 65 year old obese man with high cholesterol and a smoker


Describe the clinical presentation

- Asymptomatic to unstable angina
- Acute MI
- Ventricular arrhythmias
- Sudden cardiac death
- Asymptomatic and discovered on angiogram


Describe the diagnosis process

- Coronary Angiography
- Intracoronary imaging (IVUS, OCT, MDCT)
- These modalities have helped increase clinical recognition


What would you see on a coronary angiography?

Presence of a thin longitudinal radiolucent line representing intimal medial flap with flow in 2 or more lumens


What is the narrowing caused by?

Narrowing cause by the intramural hematoma imaging on the lumen can be misinterpreted as an atherosclerotic stenosis


When should SCAD be suspected?

In the setting of young women presenting with ACS on angio and no CAD risk factors SCAD should be suspected and IVUS or OCT should be done


What is the prognosis for patients in the hospital with SCAD?

In-hospital mortality of SCAD is relatively low
Mean rate of around 3% (0–4%)


What is the lifetime prognosis for survivors of SCAD?

- Pts who survive the acute phase have a GOOD long term prognosis
- Low recurrence rate of SCAD or ACS and a 95% 2-year survival rate


What is the overall mortality rate?

However, overall mortality in reported cases of postpartum group is 38%