3/24/16

Question 1

Aldesleukin (IL-2)

Answer 1

Renal cell carcinoma

Metastatic melanoma

Question 2

Infected T-cell cell demonstrates multilobulated nucleus described as cloverleaf of flower cells

Answer 2

HTLV-1Adult T-cell Leukemia

Question 3

Contralateral face and arm weakness of the upper motor neuron type, with gaze preference towards the side of the lesion and variable unilateral neglect

Answer 3

MCA (middle cerebral infarct)

Question 4

Excessive, intense, or prolonged grief, as well as grief that is delayed, inhibited or denied

Answer 4

Pathologic grief

Question 5

Small, gram-positive with tumbling motility

Answer 5

Listeria Monocytogenes

Question 6

Albuminocytologic dissociation

Answer 6

Elevated CSF levels of protein with normal cell count

Seen in Guillian-Barre

Question 7

Drug used to treat Chagas disease caused by Trypanosoma Cruzi

Answer 7

Nifurtimox

Question 8

Factor XI (hemophilia C) AR common in

Answer 8

Ashkenazi Jews

Question 9

Fat, elongated uvula, daytime sleepiness, inability to concentrate, and hypertension

Answer 9

OSA (obstructive sleep apnea)

Recurrent asphyxiarespiratory acidosis (if chronic)compensated by retention of renal HCO3 (metabolic alkalosis)

Question 10

Chemical antagonist-binds directly to an agonistprevents agonist binding to target
Binds toxic metal such as copper (Wilson disease)

Answer 10

D-Penicillamine

Question 11

Coltivirus

Answer 11

Double-stranded RNA virus in Reovirus family

Question 12

Primary somatosensory cortex (ex: for right side)

Answer 12

Left postcentral gyrus

Question 13

First 15 degrees of abduction of the arm

Answer 13

Supraspinatus
Most common rotator cuff injury
Pain anteriorly and superiorly to glenohumeral joint during abduction

Question 14

Seborrheic keratosis

Answer 14

Benign, flat, pigmented squamous proliferation with keratin cysts

Question 15

Dermatitis herpetiformis is associated with

Answer 15

Celiac disease (pruritic papules and vesicles)

Question 16

VTNRs (variable numbers of tandem repeats) like CAG in Huntington’s are detected by:

Answer 16

DNA-DNA hybridization

Question 17

HIV cancer associations

Answer 17

Kaposi and non-Hodgkin

Question 18

Dipalmitoylphosphatidycholine

Answer 18

Surfactant

Give mother glucocorticoids to prevent

Question 19

Serine protease inhibitor alpha-1 antitrypsin usually functions to inhibit

Answer 19

neutrophil elastase

Question 20

Faggot cells

Answer 20

APL (M3 subtype of AML)

Question 21

Most common malignancy of children?

Answer 21

ALL

Question 22

At birth all oocytes are arrested in ___________________

Answer 22

Prophase of meiosis I

Question 23

Anti-Cardiolipin antibodies are detected in syphilis (non-specific marker)

Answer 23

Cardiolipin is a phospholipid found in the inner mitochondrial membrane

Question 24

The transplant killer

Answer 24

CMV-periventricular meningeal enhancement

Question 25

Tranylcypromine

Answer 25

Non-selective monoamine oxidase inhibitor (MOA)

Question 26

Follicular thyroid carcinoma

Answer 26

``` Hematogenous spread (breaks the rule) Can go to bone ```

Question 27

A mold with septate hyphae that branch at a V-shaped 45-degree angle

Answer 27

Aspergillus fumigatus

Question 28

Cup-shaped cysts with intracystic bodies and thick cell wall

Answer 28

Pneumocystis jiroveci

Question 29

Heavily encapsulated non-dimorphic yeast that is found in soil and pigeon droppings

Answer 29

Cryptococcus neoformans

Question 30

Inheritance of G6PD

Answer 30

X-linked recessive

Question 31

The use of positive and negative consequences (reinforcement or punishment) to modify a certain behavior

Answer 31

Operant conditioning

Question 32

Low blood solubility (ex: Nitrous oxide) will rapidly induce anesthesia and patients will recover…

Answer 32

QUICKER | In contrast, high solubility (halothane) will have a longer time to induction and a slower time to recovery

Question 33

Minimum alveolar concentration

Answer 33

Potency of inhaled anesthetics Concentration of gas that is needed to eliminate movement in 50% of patients Small MAC= POWERFUL AF

Question 34

Pre-renal azotemia causes (reduced GFR)

Answer 34

Heart failure Sepsis Renal artery stenosis =Elevated BUN:Cr ratio and FeNa is less than 2% (greater would be intrinsic)

Question 35

permeability barrier in the nervous system

Answer 35

Perineurium

Question 36

Systemic retinoic acid is

Answer 36

``` CATEGORY X (3-5 weeks and woman don’t even know she Prego) Missing ears or spontaneous abortions ```

Question 37

Use of Disulfiram is an example of what type of conditioning

Answer 37

Aversive conditioning (a part of classical conditioning)

Question 38

Fetal hydantoin syndrome is due to

Answer 38

Maternal use of antiepileptic drugs such as Phenytoin

Question 39

Antineoplastic agent that is an MAO inhibitor. Patients must avoid dat cheese/tyramine to prevent HTN crisis

Answer 39

Procarbazine

Question 40

Remember you count up the reflexes:

Answer 40

Achilles reflex: S1 S2 Knee Jerk: L3 L4 Biceps: C5 C6 Triceps: C7 C8

Question 41

Long-term exercise has been shown to increase cell surface

Answer 41

GLUT-4

Question 42

IgG anti-RhD antibody that binds to and destroys RhD-positive fetal cells in the maternal circulation

Answer 42

Rhogam

Question 43

Niacin deficiency (Vitamin B3) = 3D’s

Answer 43

Diarrhea Dermatitis Dementia

Question 44

ADPKD

Answer 44

Polycystin 1 gene = Chromosome 16 Polycystin 2 gene = Chromosome 4 Symptoms: abdominal pain, hematuria, polyuria and nocturia Berry aneurysms and MVP

Question 45

DNA is transferred from one bacterium to another (direct cell to cell contact)

Answer 45

Conjugation

Question 46

Nonsmokers and woman lung cancer

Answer 46

Adenocarcinoma

Question 47

What ADR do busulfan, amiodarone, methotrexate, Nitrofurantoin, and radiation chest therapy

Answer 47

Pulmonary fibrosis

Question 48

What two viruses are NK cells most important in fighting

Answer 48

EBV Herpesviruses NK cells recognize their lesser amount of MHC I expression

Question 49

Horizontal nystagmus on lateral gaze at therapeutic levels. Vertical nystagmus, double vision, sedation, and cerebellar ataxia and tremor at supratherapeutic level

Answer 49

Phenytoin