3. Dom Lahey

Question 1

What is the general function of the immune system?

Answer 1

storage of lymphocytes, increase number of lymphocytes, provide favorable environment for establishing immunity

Question 2

Surface protection, acute inflammation, compliment process, lysosome production, and natural barriers describe what type of immunity?

Answer 2

innate

Question 3

Humoral and Cell-Mediated are 2 examples of what type of immunity?

Answer 3

aquired (adaptive)

Question 4

Response to invading bacteria, mediated by B cells/plasma cells, and involves antibody production is which form of adaptive immunity?

Answer 4

humoral

Question 5

Usually response to virus, fungi, foreign cells, mediated by T lymphocytes, does NOT depend on B lymphocyte participation, and cytotoxic response is which type of adaptive immunity?

Answer 5

cell mediated

Question 6

No/incomplete capsule, humoral immunity describes what?

Answer 6

diffuse lymphatics

Question 7

Gastrointestinal, respiratory, urogenital tracts…secretory IgA = secreted on to free epithelial surfaces (tears, saliva, gut lumen, nasal, vaginal)
- FIRST line of defense against infection (antigen specific)…what is this?

Answer 7

MALT

Question 8

Gastrointestinal tract (individual lymph nodules, Peyer’s patches)…is what?

Answer 8

GALT

Question 9

Respiratory lymph nodules, form when air tubes bifurcate…is what?

Answer 9

BALT

Question 10

Roof of nasopharynx, called Adenoids when inflamed, can cause ear-infection describes which form of tonsils?

Answer 10

pharyngeal tonsils

Question 11

Surface epithelium in the pharyngeal tonsil are what type of cells?

Answer 11

respiratory epithelium

Question 12

Boundary of oral cavity/oropharynx, partial capsule likely describes what type of tonsils?

Answer 12

Palatine Tonsils (Tonsilar Crypts)

Question 13

Surface epithelium in the palatine tonsils are what type of cells?

Answer 13

stratified squamous

Question 14

Advantages and disadvantages of the palatine tonsils are what?

Answer 14

advantages - more SA for detecting foreign antigens and lymph node formation

disadvantages - deep depressions (bacteria can thrive = infection = tonsillitis)

Question 15

The tonsil that is on the dorsal posterior 1/3 of tongue (oral cavity) is what?

Answer 15

Lingual Tonsils (Tonsilar Crypts)

Question 16

Surface epithelium in the lingual tonsils are what type of cells?

Answer 16

stratified squamous

Question 17

The tonsillar ring around openings to digestive/respiratory system is referred to as what?

Answer 17

Waldeyer’s Ring

Question 18

Which organs have a capsule, both humoral and cell-mediated immunity?

Answer 18

lymphatic organs

Question 19

Which type of lymphoid organs provide environment where lymphocytes become immunocompetent (thymus and bone marrow)?

Answer 19

primary

Question 20

Which type of lymphoid organs provide an environment where lymphocytes can contact foreign antigens and interact with each other (spleen and lymph nodes)?

Answer 20

secondary

Question 21

What is the function of the lymph nodes?

Answer 21

filtration of lymph using phagocytosis, establish humoral/CM immunity

Question 22

Which lymph node structure is described…dense irregular CT of moderate thickness (trabecular)?

Answer 22

capsule (septa)

Question 23

Which lymph node structure is described…in-coming vessels, contain valves?

Answer 23

afferent lymphatics

Question 24

Which lymph node structure is described… out-going vessels, contain valves?

Answer 24

efferent lymphatics

Question 25

Which lymph node structure is described...recessed area where efferent lymph exits, blood enters/exits?

Answer 25

Hilum

Question 26

Marginal sinus and the first to receive afferent lymph is what type of sinus?

Answer 26

Subcapsular sinus

Question 27

Which type of sinus passes thru the cortex region?

Answer 27

Cortical sinus

Question 28

Which type of sinus passes thru the deep cortex/paracortex region?

Answer 28

Deep cortical sinus

Question 29

Which type of sinus passes thru the medulla region?

Answer 29

Medullary sinus

Question 30

Regions and cells of a lymph nod, within ALL regions/sinuses are supported by system of what type of fibers and cells?

Answer 30

reticular fibers produced by reticular cells

Question 31

- Primary cell type = B lymphocyte - Activity = phagocytosis and humoral immunity (primarily IgG) This describes which part of the lymph node?

Answer 31

cortex

Question 32

AKA thymus dependent zone AKA deep cortex - Primary cell type = T lymphocyte - Activity = phagocytosis, cell-mediated immunity (long-term storage T cells) This describes which part of the lymph node?

Answer 32

paracortex

Question 33

Primary cell type = Plasma cells Activity = phagocytosis, some cell-mediated immunity * mostly humoral immunity because of ANTIBODY secretion This describes which part of the lymph node?

Answer 33

medulla

Question 34

Which structure has 2 lobes extending over the great heart vessels, primary lymphoid organ, involution starts after puberty?

Answer 34

thymus

Question 35

What organ's function is to establishment of immunocompetent T lymphocytes? It can distinguish self from non-self antigens to develop self tolerance.

Answer 35

thymus

Question 36

T lymphoblast in the thymus is called what?

Answer 36

thymocyte

Question 37

contains high cell concentration, large # of T lymphatics and macrophages, TEC types 1,2,3 * support using cytoplasmic processes, important blood-thymic barrier This describes which part of the thymus?

Answer 37

cortex

Question 38

contains lower cell density, fewer but larger T cells, macrophages, APC (dentritic cells), TEC types 4,5,6 * form thymic corpuscles This describes which part of the thymus?

Answer 38

medulla

Question 39

What cells are produced in bone marrow, enter thymus as immonincompetent cells, and then leaves bloodstream at corticomedullary line?

Answer 39

T Lymphocytes

Question 40

What area of Spleen has areas of concentrated WBCs, primarily lymphocytes?

Answer 40

white pulp

Question 41

What is the function and area of the Spleen that the white pulp is located?

Answer 41

``` Function = immunity Areas = next to capsule and setpa, splenic nodules, periarteriolar lymphoid sheaths (surround central arteries, cell-mediated) ```

Question 42

What is the area of the Spleen that is not white pulp or CT (most of spleen is RED)

Answer 42

red pulp

Question 43

What is the function of the red pulp of the spleen?

Answer 43

rapid blood filtration, contact with blood-born foreign antigens

Question 44

Caused by Epstein-Barr virus (EBV) in mucus/saliva. First replicates in nasopharyngeal epithelium, Can spread to salivary glands, lymph nodes and oropharyngeal lymphoid tissues, Then to liver, spleen, B cells, and blood. What diseases does this describe?

Answer 44

infectious mononucleosis

Question 45

Blood changes: increase in number of platelets and abnormal RBC’s and Infection: Increased risk of bacterial septicemia especially in children with Strep Pneumo These condition typically lead to what?

Answer 45

splenectomy