3. Lipids, membranes and transport Flashcards

(47 cards)

1
Q

What elements are in Lipids

A

C H O

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are lipids

A

Group of non-polar molecules
Insoluble in water
dissolve easily in organic solvents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the important groups of lipids

A

Triglycerides and phospholipids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is a triglyceride

A

Made of 3 fatty acids and 1 molecule of glycerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How is a triglyceride formed

A

Glycerol has 3 OH- groups.
Each bind to a fatty acid
Condensation reaction
Produce 3 molecules of H2O
Ester bonds between OH and COOH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is a fatty acid made from

A

A COOH- group and a long hydrocarbon chain (Unsaturated or Saturated)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Why are triglycerides not classified as polymers

A

They are not made of monomers.
They are made of 2 different types of molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the biological roles of triglycerides

A

Storage of energy
Insulation - electrical and heat
Protection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How do the structure and properties of a triglyceride relate to its function

A

High ratio of energy storing C-H bonds to C atoms = good source of energy
Low mass to energy ratio = Good storage molecules as lots of energy stored in small volume
Large, non-polar, insoluble in water molecules = no osmotic effect and dont effect water potentiels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a phospholipid

A

Lipids where one fatty acid is substituted for phosphate group
- Polar/hydrophilic head (Glycerol and phosphate)
-2 Non-Polar/hydrophobic tails (Fatty acids)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the test for lipids

A

Ethanol emulsion test
- Add ethanol to the sample to be tested
- Shake thoroughly to dissolve any lipid in sample
- Then add water to sample and shake gently
-A milky white emulsion indicates the presence of lipid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the 3 functions of plasma membranes

A
  • Control the transport of substances into and out of cell or organelle - Partially permeable
  • Act as a receptor site - Recognise chemicals that need to enter the cell
  • Separate off the cell from the environment and the different reactions - Different concs can be maintained
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What molecules do plasma membranes not let through

A

Water-soluble
Charged
Polar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What molecules are in a membrane structure

A
  • Phosphlipids
  • Membrane proteins
    -Glycoproteins
  • Glycolipids
    -Cholesterol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What do phospholipids do in the membrane structure

A

Form a bilayer
Hydrophobic tails point towards eachother
Hydrophilic head point out into the water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What do membrane proteins do in the membrane structure

A

Float about in bilayer - fluid mosaic structure
May be in one layer (Extrinsic) or across the whole membrane (Intrinsic) .
May be fixed in one place or float about
Often have hydrophilic channels in the middle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the function of an Intrinsic protein

A

Transport - channels and carriers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the function of extrinsic proteins

A

Enzymes
Receptors
Antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is a glycoprotein and its function in the membrane structure

A

Short, branching carbohydrate chains attached to proteins in the membrane.
Act as receptors for hormones and neurotransmitters or antigens

20
Q

What is a glycolipid

A

Made of a carbohydrate covalently bonded to a lipid.
Act as recognition sites
Help maintain stability of the membrane and help cells attach to one another forming tissues

21
Q

What is cholesterol

A

Restrict the movment of other molecules in the membrane
Increase the strength and stability of membranes by making them less flexible
Prevents loss of water and dissolved ions

22
Q

What is the fluid mosaic structure

A

Fluid = All different molecules can move
Mosaic = Different types of molecules. Some can float within the bilayer

23
Q

What can molecules in the plasma membrane do

A

-Move sideways
-Leave the membrane to form vesicles
-Join memranes from vesicles

24
Q

Why does should a membrane be fluid

A

Cells can change their shapes e.g phagocytes

25
What are 4 ways substances can be exchanged
Diffusion Osmosis Active transport Endo/Exocytosis
26
What is diffusion
The movement of substances from a region of higher concentration to a region of lower concentration down a concentration gradient
27
How does surface area affect rate of diffusion
The greater the surface area of the membrane over which diffusion occurs the greater the rate of diffusion
28
How does the thinckness of exchange surface affect the rate of diffusion
the thinner the surface the faster the rate of diffusion (shorter diffusion pathway)
29
How does the conc gradient affect the rate of dissusion
the steeper the gradient the faster the rate of diffusion
30
How does the size of the diffusing molecule affect rate of diffusion
the smaller the molecule the faster the rate of diffusion (can diffuse through the phospholipid bilayer easier)
31
How does temperature affect the rate of diffusuion
the higher the temperature the faster the rate of diffusion (more kinetic energy)
32
How does water solubility/ polarity affect the rate of diffusion
Molecules that are water-soluble/polar/ charged generally diffuse slower than lipid-soluble/non-polar/uncharged ones (non-polar can pass through hydrophobic region of the phospholipid bilayer easier)
33
What is Ficks law
Rate of diffusion (is proportional to) (SA x difference in conc) / thickness of exchange surface
34
How do you increase the rate of diffusion
- Maximise the SA - Maximise concentration difference - Minimise the thickness of exchange surface
35
What is simple diffusion
Diffusion of substances directly across the phospholipid bilayer Molecules that are non-polar and smaller can diffuse through
36
What is facilitated diffusion
Molecules diffuse through bilayer through intrinsic proteins. The substances are specific to the proteins Passive Moves charges, polar or hydrophilic substances. Channel proteins for ions, carrier proteins for others
37
What is osmosis
the movement of water across a partially permeable membrane down a water potential gradient from higher (less negative) to lower (more negative) water potential.
38
What is water potentiel
The tendency for water to move from one place to another Measure in KPa Pure water has WP of zero, all others are negative
39
What happens to an animal cell in a hypertonic solution
lower water potential than the cell Water leaves cell cell shrinks (crenate)
40
What happens to an animal cell in a hypotonic solution
Higher WP than cell water enters cell Cell swells and bursts - osmotic lysis
41
What happens to an animal cell in isotonic solution
Same WP as cell no net osmotic movment
42
What happens to a plant cell in hypertonic solution
Lower WP than cell Water leaves cytoplasm and vacuole Cytoplasm shrinks away from cell wall and leaves a gap Gap filled with concentrated salt solution Plasmolysis
43
What happens to a plant cell in a hypotonic solution
Higher WP than cell water enters the cell Cytoplasm and vacuole gain water Due to high tensile strength of cell wall - cell will not burst Turgid
44
What happens to a plant cell in an isotonic solution
Same WP No net osmotic movment
45
What is active transport
Needs ATP Movment against a concentration gradient Needs specific proteins carriers/ pumps Factors affecting respiration affect AT
46
When does endo/exocytosis occur
When a cell needs to transport large amounts of materials across their plasma membrane
47
What is endo/exocytosis
Cells make containers out of the plasma membrane Makes vesicles Endocytosis is importing materoials into the cell Excocytosis is exporting materials out of the cell Both require ATP