Neuology videos 15-5-14

Question 0

What is the pathogenesis of coronavirus infection in cats?

Answer 0

< 3 years old
Multi-cat household
Non-effusive
Pyogranulomatous and immune-complex-mediated vasculitis

Question 1

What are the clinical signs of coronavirus infection in cats?

Answer 1

Vestibular ataxia
Seizures
Cerebellar signs
Systemic and ocular involvement

Question 2

How is feline coronavirus diagnosed?

Answer 2

FCoV antibody titre of > 1200
Albumin:Globulin ratio
Acid glycoprotein level
Haematology - neutrophilic pleocytosis

Question 3

What is the treatment for feline coronavirus?

Answer 3

Steroids and interferon

Question 4

What is the treatment for a broken basisphenoid bone in a horse?

Answer 4

NSAIDs
IV mannitol/hypertonic saline
IV fluids
Supportive care

Question 5

What are the characteristics of GME (granulomatous meningoencephalitis)?

Answer 5

Any breed but especially toy breeds and terriers
Mean age 5 years with female predisposition
Ocular form can progress into disseminated/focal forms
Can be seen with disseminated forms

Question 6

What are the characteristics of NME (necrotising meningioencephalitis)?

Answer 6

Pug dog encephalitis, also Maltese, Shih Tzu, Lhasa apso, Chihuahua, Pekingese
6 months - 7 years, mean age 19 months, fawn coloured females
Clinical course few days to months before presentation, forebrain affected = cerebellum +/- thalamus,
Mean survival 23 days

Question 7

What are the characteristics of NLE (necrotising leucoencephalitis)?

Answer 7

1-10 years old with no sex predisposition
Yorkshire terriers and other breeds
Highly variable clinical course, usually chronic progressive affecting the forebrain and brainstem causing altered mentation, seizures, central blindness, central vestibular signs