Clinical Scenario Forebrain Diseases

Question 0

What factors need to be discussed with the owner in respect to anti-epileptic drugs?

Answer 0

Side effects
Phenobarbitone plasma level monitoring
Neutering
Haematology and biochemistry monitoring

Question 1

What drugs are licensed for use in seizures in dogs?

Answer 1

Phenobarbitone
Potassium Bromide
Imapitoin

Question 2

Why does haematology need to be regularly monitored if a dog is on anti-epileptic drugs?

Answer 2

Check for bone marrow necrosis as it is an idiosyncratic reaction of phenobarbitone

Question 3

What are the dangers of stopping anti-epileptic drugs suddenly?

Answer 3

Increased chance the dog will seizure
More difficult to get seizures back under control
If using two drugs then have to monitor for two drugs and two lots of side effects

Question 4

What is the first line anti-epileptic drug in horses?

Answer 4

Phenobarbitone and DON’T RIDE

Question 5

What factors need to be considered when caring for a seizuring dog?

Answer 5

Stop with diazepam/phenobarbitone/propofol
Cool down to prevent hyperthermia and monitor temperature
Provide oxygen
Test blood glucose