Lecture 15: Quantitative Genetics & QTL

Question 1

Define QTL?

Answer 1

Quantitative Trait Locus, they are portions of the genomes that influence quantitative traits

Question 2

What two things are required for QTL mapping?

Answer 2

• (heritable) quantitative variation

- Genetic markers (SNPS, microsats, allozymes)

Question 3

How are QTL mapped?

Answer 3

Finding the LD between the Marker and Quantitative trait, is the marker is linked to the QTL the values would shift together, if there are not linked there would not be a pattern

Question 4

How are QTLs mapped without genetic crosses?

Answer 4

Genome Wide Association Studies (GWAS), scan genome for association between a genetic marker and a gene affecting a quantitative trait.

Question 5

Define phenotypic plasticity

Answer 5

Ability to alter phenotype (physiology, behavior, morphology) in response to a change in the environment

Question 6

Define phenotype

Answer 6

Results from development of a genotype in a given environment

Question 7

What are reciprocal transplant experiments?

Answer 7

Genotype from each location are grown at each location

Question 8

Define norm of reaction

Answer 8

The array of phenotypes expressed by the same genotypes at at different environments

Question 9

What is the Bell Curve debate?

Answer 9

Traits show heritability and phenotypic means are different, does not establish genetic difference between population.