Antibacterials Flashcards

0
Q

Nucleus of cephalosporins

A

7-aminocephalosporanic acid

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1
Q

Cephalosporins not active against:

A

Enterococci

L. monocytogenes

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2
Q

Cephalosporin dosage adjustment in liver failure?

A

No, most cleared renally

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3
Q

Cephalosporin 1st gen prototype

A

Cefazolin (IV, IM)

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4
Q

1st gen cephalosporins poor activity against

A
P aeruginosa
Indole-positive proteus species
Enterobacter sp
S marcescens
Citrobacter sp
Acinetobacter sp
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5
Q

2nd gen cephalosporin prototype

A

Cefuroxime (iv, oral)

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