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REPRO II Exam 2 > Drugs for Male GU Disorders - Martin > Flashcards

Drugs for Male GU Disorders - Martin Flashcards

1
Q

glyburide

A

sulfonylurea

-increase insulin release from beta cells of pancreas

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2
Q

metformin

A

biguanide

-increase insulin sensitivity

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3
Q

most common cause of ED

A

atherosclerosis

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4
Q

alterations in sexual response

A

SSRIs
antipsychotics - phenothiazines
alcohol

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5
Q

tx of ED

A

phosphodiesterase inhibitors

PG E1 analog

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6
Q

PG E1 analog

A

alprostadil

relaxes trabecular smooth m and dilation of cavernosal arteries

  • tx for ED
  • injected along penis
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7
Q

PDE5 inhibitors

A

tx for ED

increased cGMP - more smooth m relaxation of corpora cavernosa

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8
Q

sildenafil

A

PDE5 inhibitor

viagra

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9
Q

tadalafil

A

PDE5 inhibitor

cialis

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10
Q

avanafil

A

PDE5 inhibitor

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11
Q

vardenafil

A

PED5 inhibitor

levitra

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12
Q

CI for PDE5 inhibitors

A

nitrates use - myocardial ischemia risk**

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13
Q

daily use PDE5 inhibitor

A

tadalafil

duration of action 36 hours

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14
Q

30 minute ED drugs

A

tadalafil

avanafil

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15
Q

1 hour ED drugs

A

sildenafil

vardenafil

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16
Q

adverse of alprostadil

A

penile pain

17
Q

tx male pattern baldness

A

finasteride

5 alpha reductase inhibitor

18
Q

tx of BPH

A

5 alpha reductase inhibitors

alpha1-adrenergic antagonist

19
Q

prazosin

A

short acting alpha1 antagonist

-tx for BPH

20
Q

long acting alpha1 antagonists

A

terazosin
doxazosin
alfuzosin
tamsulosin

21
Q

finasteride

A

5a reducatase inhibitor

22
Q

dutasteride

A

5a reductase inhibitor

23
Q

smooth m in prostate

A

alpha1A receptor primarily

24
Q

adverse prazosin

A

orthostatic HTN and palpitations

25
Q

abnomal ejaculation

A

with alfuzosin

26
Q

saw palmetto

A

tx of BPH

inhibit 5a reductase and inhibit DHT binding to androgen receptors

27
Q

tx urinary incontinence

A

atropine

antagonist at muscarinic ACh receptor

28
Q

oxybutynin

A

M3 selective mAChR

used in disorders of GU tract
-reduce urinary frequency

REPRO II Exam 2 (21 decks)

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