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ENGR 1 > BugsAndDrugs > Flashcards

BugsAndDrugs Flashcards

1
Q

Gram + cocci

A

Staphylococcus 

Streptococcus 

Enterococcus

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2
Q

Gram – cocci

A

Neisseria gonorrhea

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3
Q

Gram – bacilli

A

E. coli

Pseudomonas

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4
Q

Gram + anaerobic bacilli

A

Clostridia

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5
Q

Gram - anaerobic bacilli

A

Bacteroides

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6
Q

Atypical

A

Chlamydia

Mycoplasma

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7
Q

Which cell wall synthesis inhibitors are absorbed PO?

A

PCN -V 

Oxacillin , Dicloxacillin, 
Amoxicillin , Ampicillin 
___________________ 

All cephalosporins except 
- Cefazolin (1st)
, Cefoxitin (2nd) , Ceftriaxone (3rd)

____________________ 

Carbapenams 

____________________ 

Vanc except 
- when treating C.Diff

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8
Q

Sulfonamides are absorbed PO or administered IV?

A

PO

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9
Q

Drugs that distribute to CSF

A

PCN (if tissue is inflammed) , Ceftriaxone (3rd gen ceph), 
Carbapenams

___________ 

Chloramphenicol , Metronidazole , 
Sulfonamides

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10
Q

Drugs that distribute to urine

A

AG, 
FQ 
- (Cip, Levo), 
NF

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11
Q

Drugs that distribute to bone

A

Clindamycin 


Metrinidazole

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12
Q

Drugs that distribute to lungs

A

Macrolides (ACE)


FQ 
- Levo, Mox

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13
Q

Drugs that distribute to bone (Bad)

A

TCN

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14
Q

Drugs that distribute to teeth (Bad)

A

TCN

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15
Q

TCN

A

AGs

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16
Q

Drugs that contribute to 8th nerve damage (bad)

A

AGs

17
Q

Drugs that distribute to fetus (Bad)

A

Cephalosporins, 
Macrolides, (ACE), 
TCN

______________ 

Sulfonamides

18
Q

Drugs that are eliminated Non-renally can cause what 3 negative side effects?

A
  1. drug-drug interactions, 
2. genetic polymorphisms in metabolizing enzymes, ] 
3. potential for hepatotoxicity:
19
Q

List Drugs that are eliminated Non-renally

A 
D - oxycyclin 

Q - uinolones (mox) 

C - lindamycin 

R - rifampin 

I - soniazid 

M - etronidazole
 
E - rythromycin like drugs (ery and Azi are biliary excretion) 

S - ulfonamides
20
Q

Which DQCRIME drugs are inhibitors of P450?

A

Quinolones 
Erythromycin

21
Q

Which DQCRIME drugs are inducers of P450?

A

Rifampin

22
Q

Metronidazole and Erythromycin like drugs are at risk for DDI, but via different mechanisms. Explain

A

Metronidazole: drug-drug interaction with alcohol due to inhibition of aldehyde metabolism (Antabuse reaction)

Erythromycin-like: drug-drug interactions due to inhibition of P450 (Clar-Ery not Azi)

23
Q

Renally excreted drugs

A 
PCN 
Cephalosporins 

Carbapenams 

Vanc 

\_\_\_\_\_\_\_\_\_ 

AGs 

FQ (Cip, levo)
24
Q

-Cidal drugs

A 
All the CW synth inhibitors 

\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ 

Oxazolidinones for strep 

Streptogamin (whn used synergistically w/ quinupristen) 

AGs
 
\_\_\_\_\_\_\_\_\_\_\_\_ 

All inhibitors of DNA fxn
25
Q
  • Static drugs
A

Macrolides (ACE) , Clindamycin , 
Chloremphenicol , 
Oxazolidinones , 
TCN

  • Basically All protein synthesis inhibitors except: 
Oxazolidinones for strep , 
Streptogamin (whn used synergistically w/ quinupristen) , 
AGs
26
Q

Which Protein synthesis inhibitors inhibit the 30s subunit?

A

TCN


AGs

27
Q

Narrow spectrum drugs list

A

PCN 

VANC

AGs

28
Q

Extended spectrum drug list

A

Extended spectrum PCN

Anti-pseudomonal (PIP/Tazo)

Cephalosporin 
Carbapenam

29
Q

Broad spectrum drug list

A 
Macrolides
 
Chloramphenicol 

TCN 

FQ 

Sulfonamides

ENGR 1 (29 decks)

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