021615 embryology Flashcards

1
Q

sex determination occurs at

A

fertilization

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2
Q

sex differentiation occurs at

A

embryonic and into fetal period

influenced by genetic, epigenetic factors

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3
Q

Mullerian inhibiting hormone

A

promotes regression of paramesonephric (mullerian) ducts

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4
Q

where does indifferent gonad form

A

within ventromedial aspect of nephrogenic cord

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5
Q

where do primordial germ cells come from

A
yolk sac (extragonadal)
then migrate to gonad
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6
Q

when do mesonephric and paramesonephric ducts develop?

A

5th wk

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7
Q

urogenital sinus is

A

developing bladder

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8
Q

the paramesonephric duct contacts the

A

UG sinus

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9
Q

labioscrotal swellings

A

lateral to urethral (urogenital) folds

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10
Q

during wks 4-7, what happens?

A

sexually dtermined but sexually undifferentiated embryo has formed (pair of undifferentiated gonads, two sets of ducts, elevations and folds around opening of UG sinus)

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11
Q

differentiation of what occurs first?

A

gonad (wk 6-7)

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12
Q

what causes gonad development into an ovary?

A

absence of SRY gene expression

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13
Q

what causes growth and differentiation of mesonephric ducts?

A

testosterone

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14
Q

derivates of mesoneprhic duct

A

duct of epidydymis
vas deferens
ejaculatory duct
seminal vesicle

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15
Q

what interacts to form vagina?

A

paramesonephric ducts and pelvic part of UG sinus

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16
Q

UG sinus in male in the pelvic portion becomes

A

distal prostatic and membranous urethra

17
Q

phallic portion of UG sinus in male becomes

A

penile urethra

18
Q

labioscrotal folds do what in male?

A

fuse venturally to form scrotum

19
Q

how does external genitalia deveop in female direction?

A

absence of androgens

20
Q

what directs gonads to form testes?

A

SRY gene