Pharmacology Flashcards

1
Q

Antidote for Acetaminophen

A

N-acetylcysteine (replenish glutathione)

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2
Q

Antidote for AchE inhibitors (organophosphates)

A

Atropine (followed by pralidoxime)

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3
Q

Antidote for Amphetamines

A

NH4Cl (acidify urine)

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4
Q

Antidote for Antimuscarinic agents

A

Physostigmine salicylate

Control hyperthermia

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5
Q

Antidote for benzodiazepines

A

Flumazenil

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6
Q

Antidote for beta-blockers

A

Glucagon

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7
Q

Antidote for CO

A

100% O2 (or hyperbaric O2)

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8
Q

Antidote for copper, arsenic, gold

A

penicillamine

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9
Q

Antidote for cyanide

A

nitrite + thiosulfate

hydroxocobalamin

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10
Q

Antidote for digitalis

A

anti-dig Fab fragments

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11
Q

Antidote for heparin

A

Protamine sulfate

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12
Q

Antidote for iron

A

deferoxamine

deferasirox

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13
Q

Antidote for lead

A

EDTA
dimercaprol
succimer
penicillamine

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14
Q

Antidote for mercury, arsenic, gold

A

dimercaprol (BAL), succimer

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15
Q

Antidote for methanol or ethylene glycol

A

Fomepizole > ethanol; dialysis

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16
Q

Antidote for methemoglobin

A

Methylene blue

Vitamin C

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17
Q

Antidote for opioids

A

Naloxone

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18
Q

Antidote for salicylates

A

NaHCO3 (alkalinize urine)

Dialysis

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19
Q

Antidote for TCAs

A

NaHCO3 (plasma alkalinnization)

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20
Q

Antidote for tPA, streptokinase, urokinase

A

aminocaproic acid

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21
Q

Antidote for warfarin

A

Vitamin K

FFP (if bleeding)

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22
Q

Drugs that cause coronary vasospasm

A

Cocaine
Sumatriptan
Ergots

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23
Q

Drugs that cause cutaneous flushing

A

Vancomycin
Adenosine
Niacin
CCBs

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24
Q

Drugs that cause dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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25
Q

Drugs that cause torsades de pointes

A

Class III (sotalol) and Class IA (quinidine) antiarrhythmics, macrolides, antipsychotics, and TCAs

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26
Q

Drugs that cause adrenocortical insufficiency

A

HPA suppression secondary to glucocorticoid withdrawal

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27
Q

Drugs that cause hot flashes

A

tamoxifen

clomiphene

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28
Q

Drugs that cause hyperglycemia

A
Tacrolimus
Protease inhibitors
Niacin
HCTZ
Beta-blockers
Corticosteroid
(Taking Pills Necessitiates Having Blood Checked)
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29
Q

Drugs that cause hyopthyroidism

A

LIthium
Amiodarone
Sulfonamides

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30
Q

Drugs that cause acute cholestatic hepatitis (jaundice)

A

erythromycin

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31
Q

Drugs that cause diarrhea

A
Metformin
Erythromycin
Colchicine
Orlistat
Acarbose
(Might Excite Colon On ACcident)
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32
Q

Drugs that cause focal to massive hepatic necrosis

A
Halothane
Amanita phalloides (death cap mushroom)
Valproic acid
Acetaminophen
(Liver "HAVAc")
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33
Q

Drugs that cause heptitis

A

INH

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34
Q

Drugs that cause pancreatitis

A
Didanosine
Corticosteroids
Alcohol
Valproic acid
Azathioprine
DIuretics (furosemide, HCTZ)
(Drugs Causing A Violent Abdominal Distress)
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35
Q

Drugs that cause Pseudomembranous Colitis

A

Clindamycin
Ampicillin
Cephalosporins
(all predispose to superinfeciton by C. diff)

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36
Q

Drugs that cause agranolocytosis

A
Dapsone
Clozapine
Carbamazepine
Colchicine
Methimaxole
PTU
(Drugs CCCrush Myeloblasts & Promyelocytes)
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37
Q

Drugs that cause aplastic anemia

A
Carbamazepine
Methimaxole
NSAIDs
Benzene
Chloramphenicol
PTU
(Can't Make New Blood Cells Properly)
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38
Q

Drugs that cause hemolytic anemia (direct coombs positive)

A

Methyldopa

Penicillin

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39
Q

Drugs that cause gray baby syndrome

A

Chloramphenicol

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40
Q

Drugs that cause hemolysis in G6PD deficiency

A
INH
SUlfonamides
Dapsone
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin
(Hemolysis IS D PAIN)
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41
Q

Drugs that cause megaloblastic anemia

A

Phenytoin
Methotrexate
Sulfas
(Have a blast with PMS)

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42
Q

Drugs that cause thrombocytopenia

A

Heparin

Cimetidine

43
Q

Drugs that cause thrombotic compications

A

OCPs (estrogens)

44
Q

Drugs that cause fat redistribution

A

Proetase inhibitors
Glucocorticoids
(fat PiG)

45
Q

Drugs that cause gingival hyperplasia

A

Phenytoin
Verapamil
Cyclosporine
Nifedipine

46
Q

Drugs that cause Hyperuricemia (gout)

A
Pyrazinamide
Thiazides
Furosemide
Niacin
Cyclosporine
(Painful Tophi & Feet Need Care)
47
Q

Drugs that cause myopathy

A
Fibrates
Niacin
Colchicine
Hydoxychloroquine
INF-alpha
Penicillamine
Statins
Glucocorticoids
48
Q

Drugs that cause osteoporosis

A

Corticosteroids

Heparin

49
Q

Drugs that cause photosensitivity

A
Sulfonamides
Amiodarone
Tetracyclines
5-FU
(SAT For Photo)
50
Q

Drugs that cause SJS (rash)

A

Anti-epileptic drugs (ex. lamotrigine)
Allopurinol
Sulfa drugs
Penicillin

51
Q

Drugs that cause teeth discoloration

A

tetracyclines

52
Q

Drugs that cause Tendonitis, tendon rupture and cartilage damage

A

fluoroquinolones

53
Q

Drugs that cause SLE-like syndrome

A
Sulfa durgs
Hydralazine
INH
Procainamide
Phenytoin
Etanercept
54
Q

Drugs that cause cinchonism (flushed, sweaty, tinnitus, hearing loss, glurred vision)

A

quinidine

quinine

55
Q

Drugs that cause Parkinson-like syndrome

A

Antipsychotics
Reserpine
Metoclopramide

56
Q

Drugs that cause seizures

A
INH (vit B6 deficiency)
Bupropion
Imipenem/cilastatin
Tramadol
Enflurane
Metoclopramide
57
Q

Drugs that cause tardive dyskinesia

A

Antipsychotics

Metoclopramide

58
Q

Drugs that cause diabetes insipidus

A

lithium

demeclocycline

59
Q

Drugs that cause Fanconi syndrome

A

Expired tetracycline

60
Q

Drugs that cause hemorrhage cystitis

A

Cyclophosphamide
Ifosfamide
(give with mesna to prevent)

61
Q

Drugs that cause intestinal nephritis

A

Methicillin
NSAIDs
Furosemide

62
Q

Drugs that cause SIADH

A

Carbamazepine
Cyclophosphamide
SSRIs

63
Q

Drugs that cause dry cough

A

ACE inhibitors

64
Q

Drugs that cause pulmonary fibrosis

A
Bleomycin
Amiodarone
Busulfan
Methotrexate
(Breathing Air Badly from Medications)
65
Q

Drugs that cause disulfiram-like reaction

A
Metronidazole
Certain cephalosporins
Griseofulvin
Procarbazine
1st generation sulfonylureas
66
Q

Drugs that cause nephrotoxicity/ototoxicity

A

Aminoglycosides
Vancomycin
Loops
Cisplatin

67
Q

Sulfa drugs

A
Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonamide antibiotics
Sulfasalazine
Sulfonylureas
68
Q

-azole

A

ergosterol synthesis inhibitor

69
Q

-bendazole

A

antiparasitic/antihelmintic

70
Q

-cillin

A

peptidoglycan synthesis inhibitor

71
Q

-cycline

A

protein synthesis inhibitor

72
Q

-ivir

A

neuraminidase inhibitor

73
Q

-navir

A

Protease inhibitor

74
Q

-ovir

A

DNA polymerase inhibitor

75
Q

-thromycin

A

Macrolide

76
Q

-ane

A

inhalational general anesthetic

77
Q

-azine

A

typical antipsychotic

78
Q

-barbital

A

barbiturate (duratuation)

79
Q

-caine

A

local anesthetic

80
Q

-etine

A

SSRI

81
Q

-ipramine

A

TCA

82
Q

-triptan

A

5-HT 1B/1D agonist

83
Q

-tryptyline

A

TCA

84
Q

-zepam

A

Benzo (frequency)

85
Q

-zolam

A

Benzo (frequency)

86
Q

-chol

A

cholinergic agonist

87
Q

-curium or -curonium

A

non-depolarizing paralytic

88
Q

-olol

A

beta blocker

89
Q

-stigmine

A

AchE inhibitor

90
Q

-terol

A

beta2 agonsit

91
Q

-zosin

A

alpha1-antagonist

92
Q

-afil

A

PDE-5 inhibitor

93
Q

-dipine

A

Dihydropyridine CCB

94
Q

-pril

A

ACE inhibitor

95
Q

-sartan

A

Antiotensin-II receptor blocker

96
Q

-statin

A

HMG-CoA reductase inhibitor

97
Q

-dronate

A

bisphosphonate

98
Q

-glitazone

A

PPAR-gamma activator

99
Q

-prazole

A

PPI

100
Q

-prost

A

Prostaglandin analog

101
Q

-tidine

A

H2-antagonist

102
Q

-tropin

A

Pituitary hormone

103
Q

-ximab

A

Chimeric mAb

104
Q

-zumab

A

humanized mAb