HF still... 3

Question 1

NT-proBNP

Answer 1

1. N termius breakdown product of BNP
2. inactive
3. t1/2 of 120 minutes

Question 2

BNP half life

Answer 2

20 minutes

Question 3

elevations of BNP are often due to

Answer 3

HF but can also be due to sepsis of PE

Question 4

clinical, BNP is used to

Answer 4

rule out symptomatic HF

Question 5

in patients with chronic HF, and elevated BNP is

Answer 5

less useful to determine if new dysnpea is from acutre HF decompensation or from some other process (COPD exacerbation)

Question 6

what is more useful, negative or positive BNP?

Answer 6

negative because a low BNP make HF very unlikely as the cause of the symptoms

Question 7

EKG in HF

Answer 7

1. no direct diagnosis of HF
2. infer possibility of HF from other findings, like
   a. prior MI (q wave)
   b. LVH (increased voltage)
   c. diffuse conduction disease from fibrosis or myocardial damage (LBBB)
   d. arrhythmia (AFib, ventricular ectopy)

Question 8

EF =

Answer 8

end diastolic - ensystolic volume/ end diastolic volume

%

Question 9

EF is a

Answer 9

gross measure of systolic function

Question 10

examples of EF

Answer 10

1. Normal = (100 ml – 40 ml) / 100 ml = 60%
2. HFrEF = (200 ml – 150 ml) / 200 ml = 25%
3. Dilated AND reduced stroke volume