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Exercise Physiology > Muscle Physiology > Flashcards

Muscle Physiology Flashcards

1
Q

Structural Proteins

A
  • titin, desmin, vimentin, alpha actin

- hold actin & myosin & myofilaments in place

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2
Q

Contractile Proteins

A
  • Actin & myosin

- actually cause muscle contraction

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3
Q

I band

A

region of sarcomere with thin filaments only

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4
Q

H Zone

A

-region of sarcomere containing myosin only

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5
Q

Muscle cell

A

Muscle Fiber

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6
Q

T Tubule

A
  • continuation of sarcolemma that protrudes into the sarcoplasm
  • allows action potential to get to deeper into cell to release Ca++
  • between 2 lateral sacs to make a triad
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7
Q

Epimysium

A

Covers entire Mm

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8
Q

Sarcomere

A
  • made of protein filaments

- structural unit of muscle, separated by Z lines

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9
Q

Endomysium

A

-covers each muscle fiber

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10
Q

Each actin is surrounded by

A

3 myosin

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11
Q

Sarcoplasmic Reticulum

A
  • Ca++ storage in lateral sacs, close to T tubules

- Wraps longitudinally around myofibril

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12
Q

Regulatory Proteins

A
  • tropomyosin & troponin

- prevent/cause muscle contraction

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13
Q

TnT

A

(troponin)

binds to tropomyosin

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14
Q

3 classifications of Sarcomere Proteins

A
  • regulatory
  • contractile
  • structural
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15
Q

Z Line

A
  • marks boundary of sarcomere
  • connect 1 sarcomere to next
  • (actin attached here)
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16
Q

M Line

A
  • Extends through the center of the H zone

- represents proteins that serve to hold together the adjoining myosin molecules

17
Q

Muscle Connective Tissue

A
  • Epimysium
  • Perimysium
  • Endomysium
18
Q

Troponin

A
  • complex of 3 units (mickey mouse ears)
  • TnC
  • TnT
  • TnI
19
Q

Perimysium

A

covers a fasiculus

20
Q

A Band

A

-region of sarcomere containing all of the myosin and the actin that overlaps it

21
Q

The myosin is cocked when:

A

it has ADP + Pi bound to it’s head

& a high energy form of myosin

22
Q

Actin

A
  • Spherical molecules joined in 2 helical strands

- each sphere has binding site for myosin

23
Q

Mm connective tissue fuses at ends of muscles to:

A

form tendons to attach to bones

24
Q

Fasciculus

A
  • bundle of muscle fibers in parallel

- separated by perimysium

25
Q

Myofibrils

A
  • contractile unit of Mm where tension is generated

- one segment is a sarcomere

26
Q

Myosin

A

thick filament

27
Q

2 head of myosin

A
  • 1 site to bind with actin

- 1 site to bind ATP

28
Q

Thick Filaments

A

-made up of myosin

29
Q

Each myosin is surrounded by_____

A

6 different actin

30
Q

Thin Filaments

A

-made of actin, troponin, tropomyosin

31
Q

Tropomyosin

A

-long threadlike protein runs along groove made by actin
molecule strings
-Covers binding sites while resting

32
Q

Tnc

A

troponin that binds to Ca++

33
Q

TnI

A

troponin that binds to actin and inhibits binding of tropomyosin to actin

Exercise Physiology (25 decks)

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