Midterm: Arthritides Flashcards

1
Q

What are the 2 Degenerative Arthritides?

A
OA
-primary
-secondary
     -post-traumatic
     -neuropathic Arthropathy
DISH
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2
Q

What are the 3 inflammatory Arthritides?

A

RA
Seronegative Spondyloarthropathies
Septic Arthritis

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3
Q

What are the 2 CT arthritides?

A

Lupus

Progressive Systemic Sclerosis

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4
Q

What are the 3 Crystal Deposition Arthritides?

A

HADD
CPPD
Gout

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5
Q

Early OA is characterized by __ response

A

healing

  • thickening of Art. cartiage
  • increased H2O content
  • Increase rate proteoglycan synthesis

*as disease progresses, these change.

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6
Q

OA cartilage changes: Normal articular cartilage is __ an separated from underlying bone by a layer of __ cartilage. __ may migrate into fissures and produce __.

A

avascular
calcified
Fibrocytes
fibrocartilage

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7
Q

What is eburnation?

A

Smooth, polished appearance of exposed subchondral bone after art. cartilage is worn away.

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8
Q

Intervertebral Osteochondrosis: Target tissue is __. Dessication of nucleus leads to __ phenomenon in IVD space and decreased __ _

A

nucleus pulposis
vacuum
IVD height

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9
Q

Spondylosis deformans target tissue is ___. What are key findings?

A

Annular fibers

-osteophytes on endplates= SPONDYLOPHYTES

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10
Q

Hemispherical sclerosis: Type __ modic changes- relative __ of vertebral body adjacent to degenerative __ often with a __ __.

A

3
sclerosis
disc
schmorls node

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11
Q

Degenerative Spondylolisthesis: __ is intact. Vertebra moves __ secondary to degenerative remodeling of the __ joints

A

pars
forward
posterior

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12
Q

Spinal Stenosis: Acquired most often due to ___. ___ may result. __ artery supplies anterior 2/3 of cord.

A

DJD
myelomalacia
Ant. Spinal Artery

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13
Q

DJD hip: MC pattern causes narrowing of __ portion of the joint. (unilateral or bilateral). MC joint for large __ __ formation to occur.

A

superior lateral

Subchondral Cyst

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14
Q

DJD AC joint: __ formation here can create impingement on available space for __ tendon (impingement syndrome)

A

osteophyte

supraspinatous

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15
Q

Secondary DJD wrist: *not common location for DJD. __ injury may predispose. Volar Intercelated Segment instability (VISI)- indicated by volar rotation of __ and abnormal __-__ spacing angle and __-__ angle

A

ligamentous
lunate
scapho-lunate
capitolunate

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16
Q

Manifestations of DJD in hands

A

Heberden’s nodes- DIP

Bouchard’s Nodes- PIP

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17
Q

DJD of Knee- Narrowing, subchondral cysts and sclerosis on __ side of __ knee. Tibial ___ may redistribute weightbearing for improvement

A

medial
right
osteotomy

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18
Q

DISH: typically - decade. __ may result if c-spine involved. Associated with __ 20-50% of the time.

A

5-6th
Dysphagia
diabetes

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19
Q

DISH: ~ __ + HLA B-27

A

1/3

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20
Q

DISH: ~__% + HLA B-8

A

40

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21
Q

DISH- at least __ continuous levels involved. Thick flowing __ and/or __ calcification of ossification. No __ joint ankylosis. Relative preservation of __ height and no other signs of degenerative disc disease. No SI joint erosion, sclerosis, or ankylosis

A
4
anterior
lateral
posterior
IVD
22
Q

DISH: diffuse, thick calcification of ___. Involvement of T-spine may be thinner and mimic __ __

A

ALL

Ankylosis Spondylitis

23
Q

OPLL: MAy be isolated of associated with __. __ spine MC involved. C-cord compression may result in upper motor __ findings.

A

DISH
Cervical
neuron
*+ babinski, hoffman, hand clumsiness, difficulty walking due to leg spasticity

24
Q

Osteitis Condensans Illi: Usually which gender? May be uni- or bilateral, but usually __. Affects __ 1/2 of Iliac side of SI joint. __ pattern of reactive sclerosis.

A

Uni- or multiparrous women
bilateral
lower
Triangular

25
Q

Seronegative Spondyloarthropathies: Includes which disorders?

A

Ankylosing Spondylitis
Psoriatic Arthropathy
Reactive Arthritis
Enteropathic Arthropathy

26
Q

HLA-B27 levels for Ankylosing Spondylitis

A

90%

27
Q

HLA-B27 levels for Psoriatic Arthropathy

A

50%

28
Q

HLA-B27 levels for Reactive Arthritis

A

75%

29
Q

Ankylosing Spondylitis: Early changes

A

widening of SI joint space, erosions, ad predilection of the lower portion of joint,
*more change on iliac side (thinner)

30
Q

Ankylosing Spondylitis: Later changes

A

Bony fusion of Si joint

*~50% pts. fuses completely bilaterally

31
Q

Ankylosing Spondylitis: Early changes in spine often occur at __ __

A

thoracolumbar junction

32
Q

Ankylosing Spondylitis: Syndesmophytes- Describe them. Where do they attach? Bridging of the __ space, resulting in ankylosis–> Bamboo Spine

A

Thin, vertical and bilateral calcific/ossific density
Attach tojoint margin= marginal
IVD

33
Q

Ankylosing Spondylitis: Enthesopathy- iinflammation of __ and __ insertions

A

ligamentous

tendinous

34
Q

__ __ sign usually precedes syndesmophyte

A

shiny corner

35
Q

Ankylosing Spondylitis: Predisposition to __ __ spinal fracture (through disc), or advanced degenerative change in spinal joints with residual mobility- __ lesion

A

carrot stick

anderson

36
Q

Psoriasis: Where are lesions common?

A

Extensor surfaces of arms/ hands/ in eyebrows, gluteal folds

*nail changes in 80%

37
Q

Psoriasis: HLA B-27 ~__% is Si joints involved, HLA B-27 factor in __% of those with only small joint changes

A

75

30

38
Q

Psoriasis: Spine- presence of __. May be __ shaped

A

syndesmophytes

comma

39
Q

Psoriasis: hands- __ pattern- involvement of all 3 joints is common. __ joint ankylosis is almost pathognomonic. __ __ erosions and __ joints predilicted

A

ray
IP
Mouse ear
DIP

40
Q

Psoriasis: __-__ instability may occur

A

Atlanto-Axial

41
Q

Reactive Arthritis: __ factor on 80-90%. Uncommon in __ __. Involvement of __, __, and predilection for __ __ involvement.

A
HLA
African Americans
eyes
urinary tract
lower extremity
42
Q

Reactive Arthritis: __ __- calcaneal osteophyte of periostitis, subtle periostitis.

A

Lover’s heels

43
Q

Reactive Arthritis: Inflammatory erosions of small joints of feet may be seen aka __ __

A

Lanouis Deformity

44
Q

RA: __ joint disease in both upper and lower extremities. Misalignments of joints (2)

A

Erosive
Swan neck deformity
ulnar drift of MCs

45
Q

RA: Hips: __ joint space loss and erosions. __ __ may occur

A

uniform

protrusion acetabuli

46
Q

RA: Spine: MC* __ formation may stenose canal.

A

pannus

47
Q

Gout: MC joint

A

1st MCP joint

-up to 60%

48
Q

Gout: __ develops in very chronic cases (10-12 years). Defined as uric acid crystal deposition in __ __

A

tophus

soft tissue

49
Q

CPPD: AKA __ __. deposition of CPPD in cartilage of joint may result in cartilage __. What are 3 favorite sites?

A

Pseudo Gout
calcification
triangular fibrocartilage of wrist
Knee (esp. menisci)
1st and 2nd MCP
*usually bilateral, not always symmetrical
*cloud like Ca++ of synovium may occur as well

50
Q

CPPD: X ray findings: Priominent __ __ formation common. Degenerative changes to non-weight-bearing joint. Isolated ___ joint involvement also suggestive.

A

Subchondral cyst

patellofemoral

51
Q

HADD aka __ __: MC in __ tendon. Calcification develops in the relatively __ area of tendon near insertion- same place tears frequently occur

A

Calcific Tendonitis
Supraspinous
avascular

52
Q

HADD: __ hand involvement more common.

A

Dominant