Peds Pharmacology Flashcards

1
Q

Rocefin sx in children

A

jaundice

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2
Q

Erythromycin SE in children

A

pyloric stenosis

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3
Q

Don’t use Adderall with what ECG rhythm

A

prolonged QT

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4
Q

Ketoconazole SE

A

ergosterol may cause nausea/ vomitting

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5
Q

Ketoconazole not for…

A

Aspergillosis or cryptococcus or mucormycosis

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6
Q

Imipramine

A

TCA

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7
Q

Imipramine overdose

A

look for QRS widening. Tx with bicarb for acidemia

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8
Q

Ampho B

A

Amphotericin B is active against a broad array of fungi, including Candida, Aspergillus,
Zygomycetes, Histoplasma, and Coccoides immitis.

Beware hypokalemia and nephrotoxicity

Liposomal preparations of amphotericin are equally
efficacious and less nephrotoxic than the standard product

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9
Q

Opiate withdrawal syndrome

A

keep newborn for 5 days

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10
Q

side effect of hydroxyurea

A

neutropenia/ thromobocytopenia/ anemia

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11
Q

absence seizure tx

A
  1. Ethosuximide

2. Valproate

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12
Q

Partial Seizures

A
  1. Phenytoin

2. Gabapentin

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13
Q

TCA overdose tx

A

Sodium Bicarb

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14
Q

Recreational drug that causes IUGR

A

methadone (opiates)

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15
Q

Valproic acid effect on fetus

A

neural tube defects,
cleft lip or dysmorphic face

broad nasal bridge
long philtrum

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16
Q

phenytoin (hydantoin syndrome)

A

nail/digit hypoplasia

17
Q

FAS

A

smooth philtrum
small palpebral fissures
thin upper lip

18
Q

Hyperactive Moro reflex caused by what

A

cocaine

19
Q

abstinence from opiates causes

A

high-pitched cry,
tremors/seizures
sneezing

tachypnea
vomiting & diarrhea

20
Q

pt has sores from picking at it. what drug abuse

A

meth

21
Q

Phenytoin (Dilantin) SE

A

Gingival Hyperplasia

22
Q

OD Iron

A

GI Bleed
uncouples ox-phos
deposits in brain, heart, lungs
hepatic liver failure

23
Q

Fe overdose tx

A

deferoxime

24
Q

what age for doxy

A

older than 8

25
Q

tx for Bronchiolitis (RSV)

A

Pavilizumab

26
Q

tx for trans-placental Graves

A

give baby Methimazole or B-blockers. Resolves after mother’s Ab go away.

27
Q

Reye syndrome

A

microvesicular fatty infiltration of liver causing

elevated LFTs
encephalopathy
elevated PT and PTT
hyperamonemia

28
Q

Rocephin

A

interferes with bilirubin binding to albumin

29
Q

Formeterol

A

long acting B2

30
Q

Amphetamine OD tx

A

Benzos

31
Q

Valproic Acid does what to eyes

A

infra-orbital creases

32
Q

Warfarin does what to face

A

nasal hypoplasia