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Year 1 Microbiology > Viral infections of skin and soft tissue I > Flashcards

Viral infections of skin and soft tissue I Flashcards

1
Q

In which skin layer are new HPV virions forming?

A

Suprabasal

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2
Q

HPV belongs to what family?

A

Papovaviridae

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3
Q

Is HPV enveloped or non-enveloped?

A

Non-enveloped

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4
Q

What is the HPV genome?

A

dsDNA

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5
Q

What is the diagnosis for HPV warts?

A

Hyperkeratosis and koilocytes

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6
Q

What are koilocytes?

A

Cells with an aberrant, large nucleus surrounded by an unstained halo

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7
Q

What condition is characterized by large eosinophilic cytoplasmic inclusions?

A

Molluscum contagiosum (molluscum bodies)

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8
Q

Molluscum contagiosum belongs to what family?

A

Poxviridae

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9
Q

What is the molluscum contagiosum genome?

A

Large dsDNA

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10
Q

Where does molluscum contagiosum replicate?

A

Cytoplasm

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11
Q

Is HSV enveloped?

A

Yes

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12
Q

What is the HSV genome?

A

dsDNA

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13
Q

What is characteristic about chickenpox lesions?

A

Found in crops - multiple evolutionary stages in that area of the body

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14
Q

What virus is responsible for chickenpox?

A

Varicella-zoster virus

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15
Q

What is the cause of shingles?

A

Varicella-zoster virus reactivation

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16
Q

What family does varicella-zoster virus belong to?

A

Herpesviridae

17
Q

Is varicella-zoster virus enveloped or non-enveloped?

A

Enveloped

18
Q

What is the varicella-zoster virus genome?

A

dsDNA

19
Q

Where does varicella-zoster virus maintain latency?

A

Trigeminal nerve

20
Q

How many serotypes of varicella-zoster virus exist?

A

One

21
Q

How is varicella-zoster virus diagnosed?

A

Tzanck smear, ELISA, latex agglutination

22
Q

What type of vaccine is the varicella vaccine?

A

Live attenuated

23
Q

The zoster vaccine is recommended for people of what age group?

A

Over age 60

Year 1 Microbiology (42 decks)

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