10- Adrenergic Drug Flashcards
1
Q
small IV doses of Epi –>
A
b1 and b2
to increase pulse pressure, Hr, SV, CO and via B2 a decrease in resistance
2
Q
moderate doses of epi –>
A
B1/2andA1
B1 increase HR SV CO and PP
but B2/A1 contradict each other
B2 decrease TPr and decrease DBP but A1 increase TPR and increase BP
3
Q
why is the effect on beta more importannt than alpha in epi?
A
beta always has higher binding affinity
4
Q
epinephrine reversal phenomenon
**will be tested
A
if you block, a or b –> more pronounced response with remaining receptor
5
Q
contraindications for epinephrine..
A
patinets using nonselective Beta blockers
6
Q
can you use epi for anaphylaxis if pt is on nonselective b blcokers?
A
nope
7
Q
main cardiovascualr effect of NE
A
increase TPR (no b2 component unlike epi)
