1. Intro Flashcards
Hematopoietically active marrow
Red marrow
Locations of red marrow in adults
- proximal ends of long bones
- sternum
- skull
- scapulae
- ribs
- pelvis
Hematopoietically inactive inactive marrow
Yellow marrow
Yellow marrow primarily consists of
Fat cells
Regulated process of boold cell production
Hematopoiesis
Enumerate the RBC production cell line
- BFU-E
- CFU-E
- pronormoblast
- basophilic normoblast
- polychromatophilic normoblast
- orthochromic normoblast
- reticulocyte
- mature erythrocyte
3 stages of hematopoiesis
Mesoblastic: embryo
Hepatic: fetal
Myeloid: from birth to adult
Site for mesoblastic hematopoiesis
Yolk sac; aorta-gonad-mesonephros (AGM) region
When will the bone marrow become active?
5th month of gestation
Hematopoietic stage that produces all hematopoietic cell lines
Myeloid
Hematopoietic stage that produces erythroblasts, granulocytes and monocytes
Hepatic
Hematopoietic stage that produces hematopoietic stem cells, primitive erythroblasts, and fetal hemoglobins
Mesoblastic
Hormone that stimulates RBC synthesis
Erythropoietin (EPO)
EPO is produced in the
Kidneys
EPO is produced in response to
Hypoxia
