Adrenergic Antagonists / Blockers

Question 1

Adrenergic Antagonists / Blockers

Answer 1

• parasympathetic NS (PSNS) – intestines and kidneys

- vasodilation, decrease HR, bronchial constriction, pupil constriction, increased GI/GU

Question 2

Alpha Blockers

Answer 2

MOA: binds w/ alpha and blocks neurotransmitters
Indications: HTN
Contraindications: PVD, CAD, sepsis
AE’s: hypotension
Interactions: other protein bound drugs, extends therapeutic window; additive or competitive
NC’s: BP(***) and neuro

Question 3

phenalomin

Answer 3

MOA: Alpha Blocker
Indications: HTN r/t Pheochromocytoma, Extravasation of IVs Infusing Vasopressors
Contraindications: Known Drug Allergy, CAD, Sepsis
Adverse Effects: Tachycardia, Dizziness
Interactions: Alcohol, ED meds, Epinephrine

Question 4

tamsulosin

Answer 4

MOA: Alpha blocker
Indications: BPH
Contraindications: drug allergy, ED meds.
Adverse Effects: headache, anxiety, hypotension, tachycardia
Interactions: alpha blockers, calcium channel blockers, ED

Question 5

Beta Blockers “LOLs”

Answer 5

MOA: binds w/ beta and blocks neurotransmitters
Indications: stressed heart, HF, MI, HTN
AE’s: too slow: hypotension, bradycardia, hypoglycemia
Interactions: additive or competitive, antacids (take 2 hrs apart)
NC’s: blood sugar (BS), VS

Question 6

metoprolol

Answer 6

MOA: Beta 1 Blocker so it is selective and it is going to decrease stimulation to heart producing a decrease in heart rate.
Indications: Post MI, HTN, Stable HF
Contraindications: Drug Allergy, Heart Block, HF, Diabetes
Adverse Effects: Hypotension, Bradycardia, Dizziness, HF
Interactions: Cardiac Glycosides, MAOIs, Cimetidine, hydralizine, BS
Nursing Considerations: Taper doses when DC, Apical Pulse, BG, BP,

Question 7

lebertalol

Answer 7

MOA: Because it blocks both alpha and beta receptors it promotes vasodilation very quickly which is needed before permanent damage is done from excessively high

Indications: Hypertensive emergencies, IV & PO but for emergencies it is given IV

Contraindications: Drug Allergy, Asthma, cardiac failure

Adverse Effects: Dizziness, HA, fatigue, Hypotension, Bronchospasm,

Interactions: Beta Agonists (Competitive), Cimetidine (additive), Insulin (hides the hypoglycemcia), Ma huang (boost metabolism-competitive)

Nursing Considerations: BP, BS, Teaching don’t stop abruptly,

Question 8

carvedilol

Answer 8

MOA: nonselective beta blocker, Alpha one blocker, calcium channel blocker
Indications: heart failure, hypertension, angina
Contraindications: Drug Allergy, Uncompensated Heart Failure, Asthma
Adverse Effects: Dizziness, Headache, Hypotension
Interactions: Amiodarone, MAOIs, Cimetidine, Blood glucose lowering drugs
Nursing Considerations: Gradually stop, Monitor for S&S of worsening Heart Failure