Cholinergic / Agonists

Question 1

Cholinergic / Agonists

Answer 1

• PSNS: rest / digest

- stimulates acetycholine neurotransmitters

Question 2

Cholinergic / Agonists: MOA

Answer 2

mimic / facilitate acetylcholine (direct / indirect), increase GI tract / GU, saliva, slows heart and respiratory system

Question 3

Cholinergic / Agonists: Indications

Answer 3

Alzheimer’s, need to speed up GI/GU system

Question 4

Cholinergic / Agonists: Contraindications

Answer 4

GI/GU obstruction, parkinson’s

Question 5

Cholinergic / Agonists: AE’s

Answer 5

dysrhythmias, BP change, bradycardia, hypotension, increased secretions

Question 6

Cholinergic / Agonists: Interactions

Answer 6

additive or competitive

Question 7

Cholinergic / Agonists: NC’s

Answer 7

VS, GI, GU, neuro

Question 8

bethanechol

Answer 8

MOA: direct-acting cholinergic agonist
Indications: Urinary Retention & Bowel atony
Contraindications: Allergy, Obstrucion of GI/GU Tract hyperthyroidism, GI Ulcer, CAD, Parkinson’s Disease.
Adverse Effects: Syncope, Hypotension, GI upset
Interactions: Indirect acting cholinergics
Nursing Considerations: Assessment & Pt. Teaching

Question 9

donepezil

Answer 9

MOA: Cholinesterase inhibitor (Indirect Cholinergic)

-This medication prevents the breakdown of acetylcholine by blocking cholinesterase. Acetylcholine stays around longer and produces an effect longer.

Indications: Alzheimer’s Disease-early phases
Contraindications: Allergy
Adverse Effects: GI upset & ulcers, drowsiness, dizziness, insomnia, bradycardia, hypotension
Mild and usually resolve on own
Interactions: Anticholinergics, NSAIDs
Nursing Considerations: Assessments & Teaching