4.3 Flashcards

(40 cards)

1
Q

Which of the following is more likely to result from poor absorption than from inadequate nutritional intake in older adults?
folic acid deficiency
iron deficiency
vitamin B12 deficiency
) lead deficiency

A

vitamin B12 deficiency

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2
Q

What is the normal bone marrow cellularity in the population older than 65 years?
90%
70%
50%
30%

A

30%

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3
Q

Why is there a relative lymphocytosis in a 2-year-old?
An absolute neutropenia occurs.
• The absolute number of lymphocytes is increased as the immune system develops.
A greater proportion of neutrophils are marginated.
Fewer lymphocytes are marginated.

A

The absolute number of lymphocytes is increased as the immune system develops.

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4
Q

All of the following are normal peripheral blood RBC findings at birth in a full-term infant except
nucleated RBCs
Mean cell volume (MCV) less than 90 fL
reticulocytosis of 5%
hemoglobin of 20.2 g/dL

A

Mean cell volume (MCV) less than 90 fL

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5
Q

Which of the following age groups normally has the lowest mean red cell values (red cell count, hemoglobin, hematocrit)?
preterm premature
full-term newborn
normal 2-year-old child
normal 30-year-old woman

A

preterm premature

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6
Q

Iron deficiency anemia in older adults is most often a result of
poor nutritional intake of iron. malabsorption of iron.
decreased ability to transport iron because of a decrease in transferrin.
bleeding in the gastrointestinal tract.

A

bleeding in the gastrointestinal tract.

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7
Q

A normal 3-month-old boy has a hemoglobin of 11.2 g/dL. Which of the following is true about his hemoglobin? It is
• higher than that of a normal full-term newborn.
lower than that of an adult of the same age.
higher than that of a 14 year old of the same sex.
• the same as that of an adult of the same sex.

A

higher than that of a normal full-term newborn.

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8
Q

What is the most likely reason that the red blood cell (RBC) count remains elevated in a newborn for the first 2 weeks of life?
A relative loss of plasma occurs during the birth process.
) A significantly longer RBC life span increases the number of red cells in circulation.
Partial anoxia exists in utero, and erythropoietin increases.
The switch from fetal to adult hemoglobin causes the number of red cells to increase.

A

Partial anoxia exists in utero, and erythropoietin increases.

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9
Q

Why is the white count in a normal full-term newborn elevated shortly after birth?
A relative loss of plasma occurs.
• An absolute increase in neutrophils occurs.
• An absolute increase in lymphocytes occurs.
An absolute increase in both neutrophils and lymphocytes occurs.

A

• An absolute increase in neutrophils occurs.

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10
Q

Which of the following is true concerning age-related changes of hemostasis in older adults?
decreased factor VIII
decreased platelet activity
increased fibrinogen
increased fibrinolysis

A

increased fibrinogen

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11
Q

A Complete blood count (CBC) is requested on a full-term newborn girl, and the following results are obtained:
RBCs
5.07 × 1012/L
Hemoglobin
14.4
Hematocrit
44.5%
MCV
88 fL
White blood cells (WBCs)
26.8 × 10%/L
Platelets
295x 109/L
What conclusion can be made regarding these data for thislinfant?
All results are normal.
The white count is elevated.
Hemoglobin, hematocrit, and MCV are all decreased.

A

Hemoglobin, hematocrit, and MCV are all decreased.

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12
Q

What is the most likely reason that the red blood cell (RBC) count remains elevated in a newborn for the first 2 weeks of life?
•A relative loss of plasma occurs during the birth process.
•A significantly longer RBC life span increases the number of red cells in circulation.
) Partial anoxia exists in utero, and erythropoietin increases.
•The switch from fetal to adult hemoglobin causes the number of red cells to increase.

A

Partial anoxia exists in utero, and erythropoietin increases.

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13
Q

Which of the following is true concerning age-related changes of hemostasis in older adults?
decreased factor VIII
decreased platelet activity
• increased fibrinogen
increased fibrinolysis

A

• increased fibrinogen

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14
Q

Iron deficiency anemia in older adults is most often a result of
poor nutritional intake of iron.
malabsorption of iron.
decreased ability to transport iron because of a decrease in transferrin.
bleeding in the gastrointestinal tract.

A

bleeding in the gastrointestinal tract.

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15
Q

A normal 3-month-old boy has a hemoglobin of 11.2 g/dL. Which of the following is true about his hemoglobin? It is
higher than that of a normal full-term newborn.
• lower than that of an adult of the same age.
higher than that of a 14 year old of the same sex.
the same as that of an adult of the same sex.

A

lower than that of an adult of the same age.

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16
Q

An 85-year-old woman has a hemoglobin of 10.5 g/dL. This is
) high for a woman of this age.
normal for this age regardless of sex (i.e., for both male and female patients).
a sign of an underlying disease and requires further evaluation.
most likely a myelophthisic anemia.

A

a sign of an underlying disease and requires further evaluation.

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17
Q

At what age is it normal for bone marrow cellularity to be 80% to 90% (i.e., has very little fat)?
at birth
• in an 8-year-old
• in a 20 to 40-year-old
• in those older than 70 years

18
Q

Which of the following age groups normally has the lowest mean red cell values (red cell count, hemoglobin, hematocrit)?
preterm premature
full-term newborn
normal 2-year-old child
normal 30-year-old woman

A

preterm premature

19
Q

Why is the white count in a normal full-term newborn elevated shortly after birth?
A relative loss of plasma occurs.
• An absolute increase in neutrophils occurs.
An absolute increase in lymphocytes occurs.
) An absolute increase in both neutrophils and lymphocytes occurs.

A

An absolute increase in neutrophils occurs.

20
Q

Which of the following is most commonly seen in the population older than70 years?
chronic lymphocytic leukemia
chronic myelogenous leukemia
essential thrombocytosis
acute lymphocytic leukemia

A

chronic lymphocytic leukemia

21
Q

Which of the following would be a valid indication for performing a bone marrow aspiration?
iron deficiency
folate deficiency
unexpected pancytopenia
leukocytosis from a severe infection

A

unexpected pancytopenia

22
Q

For which of the following is obtaining a bone marrow core biopsy mandatory?
Anemia is suspected.
Leukemia is suspected
Megakaryocyte disorders are suspected.
Aspirate is a dry tap.

A

Aspirate is a dry tap

23
Q

The best use for bone marrow aspirate smears is
counting the differential.
determining overall cellularity. estimating fat-to-cell ratio.
evaluating for focal lesions such as lymphoma.

A

counting the differential.

24
Q

What type of preparation is preferred for bone marrow aspirates?
coverslip smears from a bone marrow fragment called a spicule
wedge smears made from the blood surrounding marrow fragments
touch preps from rolling the biopsy on a glass slide
smears of the biopsy made with an automated slide maker

A

coverslip smears from a bone marrow fragment called a spicule

25
Low power (x10) is used to count and evaluate which of the following? immature neutrophils • megakaryocytes nucleated red cells plasma cells
megakaryocytes
26
A cell is described as having an eccentric, heavily stained (condensed chromatin) nucleus with blue cytoplasm. A pale perinuclear Golgi complex is noted next to the nucleus. What is this cell? 1 / 1 point myelocyte • plasma cell lymphocyte myeloblast
• plasma cell
27
What is the most common site for bone marrow aspiration in an adult? sternum posterior iliac crest tibia ribs
posterior iliac crest
28
What stain is most commonly used for bone marrow aspirates? Prussian blue new methylene blue hematoxylin and eosin (H&E) • Wright
Wright
29
Which of the following is least helpful in evaluating bone marrow findings? differential performed on the aspirate clinical findings laboratory data from chemistry, immunology, and microbiology examination of peripheral blood
laboratory data from chemistry, immunology, and microbiology
30
A bone marrow aspirate shows copious blue granules with the Prussian blue stain. Select the correct interpretation. iron overload iron deficiency tumor cells present megakaryocytes increased
iron overload
31
A cloudy cerebrospinal fluid (CSF) is diluted 1:20. In nine large squares, 99 white cells are counted. What is the total white blood count/mm? or /uL? 99 1980 2200 22,000
2200
32
Nucleated red blood cells (NBCs) and immature white cells in a CS most likely mean bacterial meningitis. patient has NRBCs in the peripheral blood. subarachnoid hemorrhage. bone marrow contamination.
bone marrow contamination
33
What determines whether or not body fluids are diluted before counting? appearance of the fluid • type of fluid •patient's diagnosis whether or not the fluid needs to go to other sections of the laboratory for additional testing
appearance of the fluid
34
Which of the following is normal in a CSF? ependymal cells 100 white cells per mm3 blasts mesothelial cells
ependymal cells
35
Which of the following is true regarding malignant cells in serous fluids? All clumps of large cells should be considered malignant. Malignant cells in serous fluids are rarely seen. ) Malignant cells categorize the fluid as a transudate. • Care must be talen to distinguish malignant cells from clumps of mesothelial cells.
Care must be talen to distinguish malignant cells from clumps of mesothelial cells.
36
A hazy spinal fluid has 400 white cells per mm that are mostly lymphocytes and reactive lymphocytes. Which of the following is most likely? bacterial meningitis viral meningitis ) infectious mononucleosis ) multiple myeloma
viral meningitis
37
If most of the white cells are neutrophils on the previously discussed CSF, what additional test should be performed? cytology flow cytometry lactate dehydrogenase Gram stain and bacterial cultures
Gram stain and bacterial cultures
38
What determines the amount of fluid used for a cytocentrifuge preparation? type of fluid desired speed of centrifugation number of cells amount of fluid collected
number of cells
39
How must synovial fluids be handled differently than other fluids? Perform a Gram stain if bacteria are seen. Dilute the fluid if the cell counts are high. Add hyaluronidase to overcome the viscous nature of fluid. Carefully search the whole cytospin preparation for malignant cells.
Add hyaluronidase to overcome the viscous nature of fluid.
40
One clinical laboratory scientist is covering the "manual bench" in the hematology laboratory, which is where body fluid examinations are done. Just as she is preparing to go on break, she simultaneously receives two specimens, one a CSF and one a BAL fluid. Both are marked "stat." What should she do first? Analyze the BAL. • Analyze the CSF. Go on break and then return and do the BAL. Go on break and then return and do the CSF.
• Analyze the CSF