Hematology 1 Flashcards

(69 cards)

1
Q

the morphology of blood cells is important to evaluate
a. Every time a complete blood count (CBC) is requested on a patient
b. When an instrument-generated flag is obtained
c. When flag limits established by clinical laboratory scientists in the laboratory are exceeded
d. When the white count is elevated

A

when flag limits established by medical laboratory scientists

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2
Q

what cellular structures appear as granules with Wright stain
a. Ribosomes
b. golgi bodies
c. Mitochondria
d. Lysosomes

A

lysosomes

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3
Q

Proper specimen collection and patient satisfaction are components of
A) Reliability
B) Quality assurance
C) Quality control
D) Precision

A

Quality assurance

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4
Q

which of the following would most likely be associated with causing a shift in quality control for only one analyte

A

starting a new lot number of thromboplastin reagent

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5
Q

which of the following can be evaluated only through the microscopic examination of a stained blood film

A

presence or absence of cytoplasmic inclusions

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6
Q

The SD for this hemoglobin method was calculated in question 18. A delta check was obtained on day 2. Controls were run as appropriate each day and were all within limits for this procedure

A

may represent an error in patient identification

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7
Q

a clinical laboratory scientist preforms 30 replicate hemoglobin determinations on a single blood sample. When statistics are used to determine the precision of the method, the mean is 13.8 g/dL and 1 SD is 0.1g/dL. This means that 95.5% of the results on this specimen lie

A

between 13.6 and 14.0 g/dL

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8
Q

which of the following procedures is safe form the production of an aerosol mist

A

manual differentials on blood films

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9
Q

the best way to prevent errors in the laboratory is to

A

hire only well trained conscientious worker

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10
Q

a 10% solution of household bleach is used to clean contaminated surfaces in the clinical laboratory this 10% solution should be prepared

A

daily

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11
Q

the primary function of a platelets is to

A

facilitate blood clotting

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12
Q

which of the following is true regarding reference ranges

A

are ranges of values for an analyte in normal healthy people

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13
Q

which of the following is acceptable safe practice

A

Disposing of used glass slides in sharps container

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14
Q

the antinuclear antibody test is positive is almost all people who have systemic lupus erythematosus it is also positive in some patients who do not have SLE. the ant deoxyribonucleic acid test is positive only in people with SLE but not in all who do which of the following is true

A

the ANA test is a good screening test and the anti DNA test is a good confirmatory test

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15
Q

what is the most frequent cause of a needle puncture or puncture from another sharp object

A

improper disposal of needle

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16
Q

what component of the erythrocyte is most responsible for its cytoskeleton and cellular integrity

A

cytoskeletal protein

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17
Q

if the lysosomal membrane ruptures, what is the consequence to the cell

A

damages internal cell structures

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18
Q

what cellular component “directs traffic” for smooth functioning

A

Golgi complex

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19
Q

in what stage of the cell cycle dose DNA replication occur

A

S

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20
Q

if the cytoplasm of a cell is very basophilic or blue when stained with Wright stain it contains

A

large number of ribosomes

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21
Q

how dose the genetically active portion of the nuclear chromatin look when stained with Wright stain

A

diffuse, uncondensed and pale blue

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22
Q

where are surface markers that help in cell identification found

A

cell membrane

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23
Q

the nucleolus of a cell is composed of

A

RNA

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24
Q

a purchase hemoglobin standard is used to adjust a hemoglobinometer. This standard is being used as a

A

calibrator

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25
safety training must be provide and documented at the time of initial assignment and how often thereafter
annually
26
who is responsible for laboratory employee safety
all of the above
27
select the term that describes a low white blood cell count
leukopenia
28
the control values for both controls for the prothrombin test were ranging between the mean and 1 SD for the first 19 days of use, Starting on day 20, the values for both were consistently between 1 and 2 SDs
shift
29
which of the following is true regarding acceptable fire safety
tests of fire detection equipment should be conducted yearly
30
who is ultimate responsible for determining the specimen integrity before analysis
medical laboratory professional
31
personal protective clothing, which must be provided by the employer, includes
gloves
32
the tubing that brings the lyse reagent to the hemoglobin cuvette on an automated cell counter is pinched and not delivering any reagent. all hemoglobin values are greater than 20 g/dL this represents what type of error
constant systematic
33
what is the best source of information regarding the nature of a chemical and it's hazard
SDS
34
a patient's white blood cells are counted on an automated cell counter 10 times. The mean white count is 8000/mL and the SD is 300 what is the coefficient of variation (CV)
3.8%
35
which of the following groups of patients should not be included in establishing moving averages using red cells indices
chemotherapy patients
36
one of two controls that have been evaluated over the last 28 days a result on day 29 between 2 and 3 SD of the mean; the other control is within 2 SD of it mean what is the corrects procedure to follow
recalibrate the instrument
37
hematology is the study of
blood cells
38
which of following require wearing a face shield or eye goggles
cleaning up an acetic acid apill
39
what dose the CV calculated in question 2 describe about the white cell counts
precision
40
what cellular component is responsible for energy production and metabolic processes
mitochondria
41
Erythropoietin is a growth factor affecting erythroid progenitors and is produced by what organ
kidney
42
which of the following morphologic characteristics is representative of apoptosis
cell shrinkage
43
protein synthesis occurs in what part of a cell
ribosomes
44
what cellular components of the erythrocyte is its control center
nucleus
45
after birth where dose hematopoiesis predominantly occur
bone marrow
46
a cell that is actively synthesizing protein has
more nucleoli
47
lysosomes are found in the cytoplasm of many cells and contain
hydrolytic enzymes
48
protein synthesis occurs in what part of a cell
ribosomes
49
Erythropoietin is a growth factor affecting erythroid progenitors and is produced by what organ
kidney
50
why are erythrocyte cellular inclusions such as Howell-Jolly bodies found after surgical removals of the spleen
the absent spleen cannot “pit” or remove the normally formed inclusions
51
when hematopoiesis occurs in the liver in an adult it is called
extramedullary
52
all of the following functions are preformed by cytokines except
inducing macrophages to attack senescent cells
53
what condition is most associated with autosplenectomy
sickle cell anemia
54
the thymus is responsible for the initial development of
T cells
55
germinal centers in lymph nodes contain primarily
B cells
56
what is the primary mechanism for the anemia associated with kidney disease
inadequate synthesis of erythropoietin
57
why dose surgical removal of the spleen cause people to have an increased platelet count
the 30% of platelets normally stored in the spleen are freely circulating
58
which of the following is a morphologically identifiable precursor cells using Wright stain
promyelocyte
59
how many blood cells are made each day in the bone marrow of a normal adult
hundreds of billions
60
colony-stimulating factors
are produced by many cells
61
kupffer cells found in the liver are
macrophages
62
where are developing red cells located in the bone marrow
adjacent to the outer surfaces of the vascular sinuses
63
which of the following using Wright stain is a feature of normal cells as they mature
nuclear chromatin becomes more condensed
64
what are the major hematopoietic sites in the fetus and in the adults
fetus liver / adult bone marrow
65
which of the following is a hematopoietic growth factor
interleukin
66
how do cells get from the bone marrow into peripheral circulation
mature cells squeeze through spaces in the vessel endothelial lining
67
enlarged lymph nodes are commonly found in all of the following except
liver cirrhosis
68
apoptosis is
programmed cell death
69
what bone marrow cells can differentiate into all of the blood cells
hematopoietic stem cells (HSCs)