40: Acute Leukemias - Hilgerson

Question 1

more predominant in adults: AML or ALL

Answer 1

AML

80% of leukemias

greater than 60 yo

Question 2

atomic bomb survivors and radiation therapy and chemotherapy might lead to..

Answer 2

AML

myeloproliferative or myelodysplastc syndromes can lead to AML as well

Question 3

typical presentation of AML ***

Answer 3

malaise 
pallor
weight loss
fever and 
BLEEDING (unusual bruises, etc)

Question 4

those with treated AML usually die of …

Answer 4

INFECTION (70%) ***

Question 5

look for _____ on peripheral smear for AML

Answer 5

auer rods***

auer rods = ana

looks like splinters on edge of cells

Question 6

epidemiology of ALL

Answer 6

primarily a disease of kids, less than 20% of adult leukemias

Question 7

bleeding could be AML but it could also be

Answer 7

ALL

ALL has more often CNS meningeal involvement (stiff neck, papilledema, etc)

Question 8

two Ls in ALL =

Answer 8

more lymphadenopathy

also hepatosplenomegaly

Question 9

if you are going to get ALL, when would be best?

Answer 9

better in children, much worse in infants and adults

Question 10

the slide of ALL looks like…

Answer 10

variation in size and shape of the cells don’t see anything in the cells
“bingo markers”

Question 11

neurologic finding including aletered emtnal status, seizure, etc are more common in …

Answer 11

ALL