47: Lymphoproliferative Disorders - Kanis

Question 1

multiple myeloma - CRAB

Answer 1

hyper calciumemia
renal failure
anemia
lytic bone lesions

Question 2

test of choice for multiple myleoma

Answer 2

SPEP serum prtn electrophoresis

diagnosis is suggested by presence of M prtn, plasmacytosis, and myeloma related organ or tissue involvement

Question 3

** multiple myeloma has…

Answer 3

hypercalcemia
lytic bone lesions
rouleaux formation
Beta2 microglobulin

Question 4

*** MGUS?

Answer 4

benign disorder
absence of organ or tissue involvement

diagnosis of exclusion:
no anemia
normal calcium levels
no bony lesions

Question 5

monoclonal gammopathy involving IgM

Answer 5

waldenstrom

associated with hyperviscosity syndrome

Question 6

extracellular accumulation of insoluble prtn fibrils

Answer 6

amyloidosis

AL amyloidosis is a plasma cell disorder involving the accumulation of light chains in the body

Question 7

stain tissue with _____ to see amyloidosis fibrils

Answer 7

congo red