Male repro 2 Flashcards

1
Q

name the two components of the intratesticular duct system

A
  • intratesticular

- extratesticular

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2
Q

components of the intratesticular duct system

A

-seminiferous terminus, straight tubules, rete testis

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3
Q

components fo the extratesticular duct system

A
  • efferent ductules,
  • duct of epididymis
  • ductus deferens
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4
Q

what cell type is found in the seminiferous tubule terminus

A

-sertoli cells only

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5
Q

rete testis

  • epithelium characteristics
  • function
A
  • simple cuboidal epithelium
  • many microvilli
  • fluid resorption to concentrate sperm
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6
Q

efferent ductules

  • epith
  • lumen characteristics
  • function
A
  • speudostratified columnar
  • short cells with microvilli
  • tall ciliated cells which transport the non-motile sperm
  • star shaped lumen
  • surrounded by smooth muscle
  • resorbs most of the fluid from testis
  • cilia are unique to the male repro tract
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7
Q

duct of the epididymis

  • type of duct
  • epithelium
  • cell type found
A
  • long coiled tube
  • pseudostratified columnar
  • principal cells
  • basal stem cells
  • smooth apical surface cells
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8
Q

principal cells of the epididymis

A

-tall and possess stereocilia

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9
Q

functions of the epididymis ducts

A
  • absorb fluis and debris, residual bodies
  • secrete products for sperm maturation (forward mobility protein )
  • smooth muscle (1 layer proximally and 3 toward the tail)
  • transit through tubules is about 12 days
  • tail stores sperm prior to ejaculation
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10
Q

ductus (vas) deferens

A
  • pseudostratified columnar with long microvilli
  • basal (stem) cells
  • single lumen not as smooth as epididymis ducts
  • three smooth muscle layers that contract during ejaculation (LCL)
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11
Q

seminal vesicle

  • tube type
  • mucosa characteristic
  • epithelium
A
  • coiled tube
  • highly infolded mucosa
  • pseudostratified columnar with basal stem cells
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12
Q

secretions of the seminal vesicles

A
  • fructose
  • flavins (visible in UV light)
  • prostaglandins
  • seminogelins 1 and 2 (cause the semen to be viscous when initially ejaculated)
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13
Q

what types of contractions happen during ejaculation?

A
  • smooth muscle

- 60% percent of the ejaculate comes from the seminal vesicles

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14
Q

prostate

  • gland type
  • epithelium
  • what surrounds the glands?
A
  • tubuloalveolar glands
  • pseudostratified columnar
  • fibrous stroma surrounds
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15
Q

prostate secretions

  • characteristic
  • type of exocrine release
  • molecules
A
  • alkaline fluid
  • apocrine
  • fibrinolysin (serine protease which liquifies the semun shortly after ejeaculation)
  • citric acid
  • zinc (inhibits wbc’s)
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16
Q

corpora maylacea

A
  • form over time and are characteristic of prostate glands
  • precipetates may clacify
  • if enlarged it may block the ducts but this is normal
17
Q

how can you detect prostate cancer

A

-prostate cancer cells do not express p63 which is extensively expressed in normal cells

18
Q

four zones of the prostate

A
  • central
  • peripheral
  • transitional
  • periurethral
19
Q

central zone of the prostate

A

-25% of the glans, resistant to carcinoma and inflammation

20
Q

peripheral zone of the prostate

A

-70% of the gland, most of the carcinomas areise here; palpable by digital rectal exam

21
Q

transitional zone of the prostate

A

-location of BPH: benign hypertrophy/hyperplasia proliferation of stromal andglandular tissue

22
Q

periurethral zone of the prostate

A

-location of BPH

23
Q
bulbourethral glands (of cowper)
-secretions
A
  • secrete alkaline mucus
  • this is the pre ejaculate secretion
  • neutralizes any residual urine in urethra
24
Q

urethral glands (of Littre)

  • where
  • secretions
  • function
A
  • line the urethra
  • mucous producing
  • protect urethra from urine
25
Q

erectile tissue

  • consists of
  • vessels
A
  • fibromuscular CT
  • contains cavernous spaces
  • contains helicine arteries with valve-like intima cushion
26
Q

helicine arteries of the erectile tissue

A
  • have a valve-like intima cushion
  • smooth muscle cushion relaxes (permitting blood flow where it enters the cavernous spaces) following NO release from parasympathetic NS and subsequent cGMP production
  • cavernous spaces fill with blood sufficiently to compress venus plexus leading to erection