Acylation DH Flashcards

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1
Q

What is the acyl group?

A

R-C=O

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2
Q

What is the formula for ethanoyl chloride?

A

CH3COCl

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3
Q

Is the carbonyl group attacked by an Electrophile or a Nucleophile?

A

A Nucleophile

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4
Q

What’s the name of the mechanism for ethanoyl chloride and water?

A

Nucleophilic addition-elimination

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5
Q

Why use ethanoic anhydride in manufacturing over ethanoyl chloride?

A

Its cheaper
Its less corrosive
It doesn’t readily react with water
Its safer as no hydrogen chloride produced

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6
Q

What is the product if the nucleophile is ammonia?

A

An amide

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7
Q

What is the product is the nucleophile is a primary amine?

A

An N-substituted amide

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8
Q

What is the product is the nucleophile is the -OH group of an alcohol?

A

An ester

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9
Q

What is the product is the nucleophile is water?

A

A carboxylic acid

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