Acylation DH Flashcards
1
Q
What is the acyl group?
A
R-C=O
2
Q
What is the formula for ethanoyl chloride?
A
CH3COCl
3
Q
Is the carbonyl group attacked by an Electrophile or a Nucleophile?
A
A Nucleophile
4
Q
What’s the name of the mechanism for ethanoyl chloride and water?
A
Nucleophilic addition-elimination
5
Q
Why use ethanoic anhydride in manufacturing over ethanoyl chloride?
A
Its cheaper
Its less corrosive
It doesn’t readily react with water
Its safer as no hydrogen chloride produced
6
Q
What is the product if the nucleophile is ammonia?
A
An amide
7
Q
What is the product is the nucleophile is a primary amine?
A
An N-substituted amide
8
Q
What is the product is the nucleophile is the -OH group of an alcohol?
A
An ester
9
Q
What is the product is the nucleophile is water?
A
A carboxylic acid
