Insulin Flashcards

1
Q

what type of hormone is insuline

A

anabolic: increase synthesis of glycogen, lipids and proteins,

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2
Q

what stimulates insulin production and release

A

rise in serum glucose levels, glucagon

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3
Q

what inhibitis insulin release

A

low serum glucose, somatostatin

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4
Q

what does insulin inhibit

A

glycogenylysis, hepatic ketogenesis and gluconeogenesis in the liver, and peripheral tissues

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5
Q

what stimulates glycogen breakdown

A

absensce of insulin , presence of glucagon

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6
Q

when does glucagon show up

A

when blood glucose is low

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7
Q

howdoes insulin inhibit fat breakdown

A

inhibitin intracellular lipase within adipocytes, it also promotes tiglyceride storaege

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8
Q

how can insulin be given?

A

Never oral, but SQ, IM, IV, nasal

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9
Q

who uses insulin

A

All Type I diabetics, Type II when other factors have failed to control blood glucose

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10
Q

what are the 4 methods of action for insuin

A

Rapid, short, intermediate, and long

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11
Q

Rapid acting insulin

A

Lispro/aspart

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12
Q

Timing of lispro/aspart

A

15min/30-60/3-5 hrs

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13
Q

Short acting insulin

A

Regular/humulin R

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14
Q

timing of Regular humulin R

A

30min/2-4hrs/4-12hrs

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15
Q

Intermediated acting insulin

A

NPH/humulin N

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16
Q

timing of NPH/Humulin N

A

1-3hrs/6-12hrs/14-16hrs

17
Q

Long acting insulin

A

Glargine/lantus

18
Q

timing of Glargine/lantus

A

4-6hrs/flat/18-24hrs

19
Q

typical dose of insulin

A

.4-.6units reglar per kg per day in divided doses.

20
Q

when is lispro dosed

A

15 minutes before each meal.

21
Q

what drug is used during sleeping hours

A

Lantus

22
Q

what is the most feared sided effect if insulin

A

hypoglycema that can resuld in seizures coma and death

23
Q

common side effect of beginning insulin treatment

A

Weight gain

24
Q

what causes hypokalemia after insulin administration

A

potassium entry into cell from serum is stimulated

25
Q

what can happen at injection site/3

A

fibrotic/muscle or fat atrophy