4B Flashcards
(24 cards)
Hardy–Weinberg formula valuable?
calculating changes in allele frequencies
If you totalled the frequencies for all of the alleles for a given gene found within the same population, the total would equal:
1
The allele frequencies that typify a population of organisms at any one point in time constitute the _____ of that population at that time.
Genetic structure
Separation of alleles corresponds to the separation of:
Homologous chromosomes
Consider a population of 100 individuals. For a trait expressing simple dominance, genotype frequencies are W/W = 0.1, W/w = 0.7, w/w = 0.2. What are the allele frequencies of the W and w alleles in this population (where p is the frequency of the dominant allele).
p = 0.45, q = 0.55
HW principle
there is no change in allele frequency if evolution does not occur
Hardy-Weinberg conditions
no mutation, large population. no natural selection (differential survival), no migration/gene flow, no genetic drift, random mating
Hardy-Weinberg equilibrium equation for allele frequency
p+q=1
Hardy-Weinberg equilibrium equation for genotype frequency
p^2+2pq+q^2=1
HWE randomness
probability of two independent events occurring together is the product of their individual probability. no selection at genotype level since haploids mix randomly.
frequency of allele is
occurances/2
Segregation results from:
The assignment of only one allele of a gene to each gamete
Which is the only assumption of the Hardy-Weinberg model, that, if violated, generates novelty (new traits) within a population of organisms?
No mutation
A requirement for a population to remain at Hardy-Weinberg equilibrium for any particular gene is:
A large number of individuals making up the population
Imagine that you compared the observed genotype frequencies in a population to the expected genotype frequencies under Hardy-Weinberg equilibrium using a Chi-squared test and obtained a Chi-squared value of 1.32. If the critical value of the Chi-squared test statistic is 3.84 (at p = 0.05), what can you safely conclude about this population:
It is at Hardy-Weinberg equilibrium
Blending inheritance
Stabilizing selection
favors the average (intermediate) traits and selects against the extreme traits.
What major outcome of his experiments did Mendel expect to find?
Patterns of inheritance that could be explained by simple statistics
Polymorphism
🧠 Quick distinction:
If only one form is common → monomorphism.
If two or more forms are common → polymorphism.
In short:
Polymorphism = “multiple normal versions co-existing in the same group” 🌈
A heterozygote has:
Two different alleles of the same gene, on homologous chromosomes
what major outcome of his experiments did Mendel expect to find?
Patterns of inheritance that could be explained by simple statistics
formula for finding allele frequencies vs gentype frequencies
1)p+q=1
2)p^2+2pq+q^2=1