5: bacterial Flashcards

(155 cards)

1
Q

increased risk of impetigo in adults with

A

HIV, diabetes, dialysis

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2
Q

most common impetigo; cause and appearance

A

nonbullous most common
strep pyogenes + staph aureus
cornflakes glued to skin

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3
Q

bullous impetigo cause and age

A

more in newborns; caused by staph aureus

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4
Q

erysipela eponym

A

saint anthony’s fire

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5
Q

erysipela most common location

A

leg associated with athlete’s foot (tinea pedis)

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6
Q

facial erisypelas ddx

A

lupus, melasma, angioedema

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7
Q

erisypela skin texture

A

peau d’orange

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8
Q

scarlet fever tongue

A

white strawberry first 2 days

red strawberry days 4-5

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9
Q

scarlet fever skin rash description

A

subnurn with goose pimples (erection of hairs_’ also sandpaper rash

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10
Q

sanpaper rash

A

scarlet fever

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11
Q

orange peel skin infection

A

erysipelas

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12
Q

pastia’s lines

A

red streaks in skin folds 2/2 vessel fragility in scarlet fever

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13
Q

red streaks in scarlet fever

A

pastia’s lines

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14
Q

tonsillar concretions why

A

keratin, bacteria, foreign material

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15
Q

dystrophic calcification in tonsil

A

tonsillolith, calcified concretions

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16
Q

diphtheria caused by

A

C diphtheriae (Klebs-Loffer)

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17
Q

primary syphilis lesion

A

chancre

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18
Q

secondary syphilis lesions

A

skin rash, mucous patches, condyloma lata

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19
Q

condyloma lata syphilis stage

A

2

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20
Q

mucous patches syphilis stage

A

2

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21
Q

chancre syphilis stage

A

1

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22
Q

skin rash syphilis stage

A

2

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23
Q

mucous patch over oral commissure

A

syphilis stage 2, split papules

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24
Q

split papules syphilis stage

A

2; mucous patches on commissures

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25
widespread secondary syphilis when and name
lues maligna, especially in HIV+
26
pupil does not react to light infection
Argyll-Robertson, tertiary syphilis
27
glossitis in tertiary syphilis
interstitial glossitis/lobulated tongue
28
glossitis syphilis stage
3
29
luetic glossitis
atrophy and loss tongue papillae
30
congenital syphilis triad
hutchinson's teeth, ocular keratitis, eighth nerve deafness
31
initial response to tx in syphilitic pts
Jarisch Herxheiner -- fever, malaise, headache, exacerbation of skin lesions
32
infection with gonorrhea during childbirth
gonococcal ophthalmia neonatorum
33
complication of gonorrhea in women
pelvic inflammatory disease
34
muultiple small foci of TB
miliary TB
35
TB vs pneumonia
TB low grade fever vs pneumonia high
36
skin involvement in TB
lupus vulgaris
37
lupus vulgaris
skin involvement in TB
38
wasting syndrome in TB
consumption
39
calcified cervical TB LN
scrofula
40
scrofula
calcified cervical TB LN
41
false negative PPD settings
HIV+, sarcoidosis, Hodgkins, measles
42
TB tx
isoniazid, rifampin, pyrazinamide
43
two forms of leprosy
tuberculoid (localized/paucibacillary) and lepromatous (diffuse/multibacillary/nerve involement, leonine fascies, collapse of nose bridge, oral lesions)
44
oral lesions which leprosy
diffuse/lepromatous
45
facies leprosa why
bone destruction | atrophy of anterior nasal spine, maxillary alveolar ridge, endonasal infalmmation
46
lepra cells
vauolated histiocytes, mainly multibacillary lepra
47
noma agents
fusobacterium necrophorum and Prevotella intermedia
48
noma causes/settings
measles, leukemia, AIDS | poor OH, poverty, malnitrition
49
actinomyces 2 species
israelii and viscosus
50
forms of actinomycosis
cervicofacial, abdominopelvic, pulmonary
51
sulfur granules agents
actinomycosis and botryomycosis (S aureus infection)
52
cat scracth disease agent
bartonella henselae
53
bartonella henselae causes
cat scratch disease and bacillary angiomatosis
54
cat scratch disease associated syndrome
oculoglandular syndrome of parinaud | conjunctival granuloma and periauricular lymphadenopathy
55
conjunctival granuloma and periauricular lymphadenopathy
oculoglandular syndrome of parinaud | cat scratch disease associated
56
oculoglandular syndrome of parinaud
conjunctival granuloma and periauricular lymphadenopathy | cat scratch disease associated
57
bacillary angiomatosis agent
bartonella henselae
58
scarlet fever why rash
bacterial toxins attack blood vessels
59
cause of scarlet fever
group A beta hemolytic streps
60
pastia's lines
red streaks in skin folds in scarlet fever
61
tonsillitis most commonly 2/2
viral (70%)
62
cause of diphtheria
corynebacterium diphth
63
bull neck
edematous neck in diphth
64
mucous patches of syphilis histo
exocitosis adn spongiosis
65
widespread secondary syphilis
lues maligna
66
gumma histo
granulomatous inflammation
67
gumma most common sites
palate or tongue
68
tongue in 3ry syphilis
``` interstitial glossitis (lobulated, lingula muscles contract after healing of gummata) luetic glossitis -- diffuse atrophy and loss of tongue papillae ```
69
congenital syphilis triad
hutchinsons teeth, ocular keratiis (opacified cornea) eighth nerve deafness
70
mulberry molars other names
fournier's or moon molars
71
congenital syphilis 4 non-triad features
frontal bossing, short mx, high arched palate, saddle nose
72
saber shin feature of infx
syphilis | anterior bowing of tibia 2/2 periostitis
73
rhagades
perioral fissuring in syphilis
74
unilateral enlargement of clavicle infection and name
higoumenakis sign in syphilis
75
higoumenaki sign
syphilis | unilateral enlargement of clavicle
76
perioral fissuring in suphilis
rhagades
77
painless synovitis and enlargement of joints in syphilis
clutton's joint
78
clutton's joint
painless synovitis and enlargement of joints in syphilis
79
stains for syphilis
warthin starry or steiner (silver)
80
serology for syphilis
VDRL, RPR, FTA-ABS (best)
81
antibiotic adverse reaction in syphilis
Jarisch-Herxheiner reaction: secondary release of endotoxin when abx kill large numbers of bacteria fever, malaise, headache, exacerbation of skin lesions
82
fever, malaise, headache, exacerbation of skin lesions in pt given penicillin for syphilis
Jarisch-Herxheiner reaction: | secondary release of endotoxin when abx kill large numbers of bacteria
83
Jarisch-Herxheiner reaction
secondary release of endotoxin when abx kill large numbers of bacteria fever, malaise, headache, exacerbation of skin lesions
84
most common reportable bacterial infx in US
neisseria gonorrhear
85
racial gonorrhea
19x more common in AA
86
symptoms in M vs F gonorrhea
80% F asymptomatic | 10% M asymptomatic
87
site of infx in M vs F gonorrhea
M urethra | F cervix
88
significant complication of gonorrhea in F
pelvic inflammatory disease | uterus and ovarian tubes
89
disseminated gonorrhea
papules and pustules with hemorrhage in skin of extremities
90
oral gonorrhea
NUG-like but no odor | aphthae in soft palate and oropharynx
91
NUG-like but no odor
oral gonorrhea
92
gonorrhea in infant during birth
goncoccal ophthalmia neonatorum
93
oral TB; locations for primary and secondary
chronic painless ulcer (rarely also nodular, granular, or leukoplakic) primary -- gingiva, mucobuccal fold, exo site seconday - tongue, palate, lips
94
histo term for TB granuloma
tubercle
95
TB stains
acid fast and ziehl nielssen
96
what does PPD test indicate
exposure to TB
97
false negative PPD possible in who
HIV+, sarcoid, Hodfkin, measles
98
TB tx
isoniazid+rifampin +pyrazinamide +ethambutol
99
vaccine against TB
BCG (bacille calmet-guerin)
100
scrofula infected by what
m bovis --> enlargement of oropharyngeal and cervial LN, can become calcified
101
leprosy types
tuberculoid - localized - usually paucibacillary | lepromatous - diffuse - usually multibacillary
102
multibacillary leprosy face and mouth
leonine facies, collapse of nose bridge, yellow/red oral papules that ulcerate
103
facies leprosa look and reason
triad: atrophy of anterior nasal spine, atrophy of mx alveolar ridge, endonasal inflammation 2/2 bone destruction
104
leprosy teeth
pulp involvement --> vascular damage --> red discoloration of crown
105
which form of leprosy has granulomas
only tuberculoid; few bacilli
106
lepra cells
multibacillary lepra vacuolated histiocytes rich in bacilli
107
special stain for lepra
acid fast, Fite method
108
tx for lepra
rifampin
109
NOMA causative
fusobacterium necrophorum and prevotella intermedia
110
NOMA inciting factors
often preceded by measles also herpes, varicella, scarlet fever, TB, gastroenteritis, bronchopneumonia AIDS, cancer, poor OH, poverty, malnutrition etc
111
actinomycosis organisms and staining
A israelii and A viscosus | G+, silver+
112
colonies of actinomyces in tonsillar crypts
concretions
113
actinomycosis locations
55% cervicofacial 25% abdomino pelvic 15% pulmonary then other (skin, ileocecal, GU)
114
sulfur granules what are and seen in
large yellow flecks = colonies of bacteria ``` actinomycosis and botryomycosis (S aureus) ```
115
large yellow flecks which infx
``` actinomycosis and botryomycosis (S aureus) ``` bacterial colonies aka sulfur granules
116
botryomycosis histo
abundant necrosis with admixed basophilic concretions surrounded by eosinophilic band (Splendori-Hoeppli phenomenon: in vivo formation of eosinophilic material around microbes)
117
splendori-hoeppli phenomenon
eosinophilic band around basophilic concretions | botryomycosis
118
actino clinical (location and look)
wooden induration of angle of MD with abscess and sinus tract also tongue, subMD gland, parotid poss osteomyelitis, tonsillar hyperplasia periapical; and in cysts
119
special stains for actino
Grocott methenamine silver | Brown and Brenn
120
cat scratch dz causative
bartonella henselae and quintana
121
most common cause of chronic regional LAD in children
cat scratch dz
122
cat scratch dz clinical - and oral
papule/pustule along scratch line 50% single LN involvement if oral: mass in buccal mucosa consider also: oculoglandular syndrome of parinaud conjunctival granuloma and preauricular LAD
123
oculoglandular syndrome of parinaud
conjunctival granuloma and preauricular LAD in cat scratch dz
124
conjunctival granuloma and preauricular LAD
oculoglandular syndrome of parinaud cat scratch dz
125
cat scratch dz histo and stains
granulomatous infalmmation with central stellate abscess | warthin starry or Brown Hopps
126
bacillary angiomatosis cause and mech
bartonella henselae | subQT vascular proliferation
127
bacillary angiomatosis clinical and histo ddx
clinical ddx from Kaposi | histo similar to histiocytoid hemangioma
128
sinusitis most common cause and predisposing factors
blockage of ostiomeatal complex presidposing: recent upper respiratory viral infx and allergic rhinitis
129
bacteria in acute sinusitis
S pneum, H influ, Moraxella catarrhalis
130
klebsiella infx of nasal cavity
rhinoscleroma
131
rhinoscleroma
klebsiella infx of nasal cavity
132
phases of rhinoscleroma
rhinitic, florid, fibrotic
133
rhinoscleroma clinical
anesthesia of soft palate, uvula hypertrophy | hebra's nose -- destruction of nasal cartilage with formation of nodules
134
destruction of nasal cartilage with formation of nodules
hebra's nose in rhinoscleroma (klebsiella)
135
hebra's nose
destruction of nasal cartilage with formation of nodules in rhinoscleroma (klebsiella)
136
special cells in rhinoscleroma; general histo and stains
Mikulicz -- large m/ph with clear vacuolated/foamy c/pl seen in association with plasma cells, lymphocytes, and fibrosis (late stage) warthin starry (best), Giemsa, gram
137
rhinoscleroma ddx
leprosy (need acid fast), TB, PCM, extranodla Rosai-Dorfman
138
most common vector borne illness in US
Lyme dz - through deer tick -- Borrelia burgdorgferi
139
borrelia burgdorferi
lyme dz
140
bartonella
cat scratch and bacillary angiomatosis
141
lyme dz classic clinical
erythematous papular rash of extremities (erythema migrans) | can involve joints, heart, CNS
142
group and infx of strep pyogenes
group A beta hemolytic strep impetigo, erysipelas, scarlet fever
143
calssic group a beta hemolytic strep
pyogenes
144
corynebacterium morphology and toxin
gram + rod | exotoxin --> necrosis
145
diphtheria clinical + organ damage
pseudomembrane on tonsils LAD bull neck damages heart, kidney
146
neisseria morphology and culture conditions
G- coffee bean diplococci chocolate agar + CO2 aerobic
147
mycobacterium leprae aka, morphology, oxygen other names for disease
Mycobacterium leprae ( Hansen’s bacillus spirilly )  Aerobic rod shaped Leprosy ( Hansen disease)
148
noma agents
Fusobacterium necrophorum | Prevotella Intermedia
149
st anthony's fire seen in x3
1- Erysipelas 2- Ergotism 3- Herpes zoster
150
diseases with saddle nose
``` 1-Syphilis 2-Leprosy 3-Wegeners 4- Polychondritis 5-Drug abusers (cocaine) 6- α-mannosidosis ```
151
+ve lepromin test eponymous rxn
Mitsuda rxn - | = intradermal injection of armadillo-derived lepra bacilli
152
risks with chronic cutaneous lepra lesions
SCC
153
stellate abscess
cat scratch bartonella
154
cat scratch stains
Brown Hoppe and Warthin Starry
155
noninvasive mycetoma causative
aspergillus fumigatus -- antroliths and chronic sinusitis