5 Endocrine Disorders Flashcards

(51 cards)

1
Q

What is the other name for Type 1 diabetes (advanced disease)?

A

Juvenile Diabetes

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2
Q

Type 1 is _____ controlled

A

Insulin

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3
Q

Concerns with Type 1 diabetes in pregnancy

A

Growth factos
poor vascularization to placenta
Increased resistance at placental bed

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4
Q

Diabetes Type 1 is a ______ abnormality

A

Congenital

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5
Q

What disrupts organogenesis

A

Hyperglycemia

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6
Q

What are the MOST COMMON DEFETS in Diabetes Type 1

A

Cardaic defects

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7
Q

What are the OTHER defects in Diabetes Type 1 (6)

A
Skeletal (caudal dysplasia sequence)
CNS
Renal
GI
IUGR
Macrosomia
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8
Q

Mothers with Type 1 diabetes has a history of (4)

A

Spontaneous abortions
IUGR
Intrauterine deaths-stillbirths
Neonatal deaths

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9
Q

The most severe form of caudal regression syndrome

A

Sirenomelia aka Mermaid syndrome

sacral agenesis, lower thoracis spine agenesis, hypoplastic femurs, VACTERL

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10
Q

Type 1 diabetes and _______ intolerance is critical to control in ______ pregnancy

A

glucose; early

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11
Q

Controlling glucose in early pregnancy decreases the risk of?

A

congenital abnormalities

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12
Q

If glucose levels are elevated in later pregnancy can result in

A
Macrosomia
Anoxia due to pre-clampsia
IUGR
Primary fetal hazard
stillbirth
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13
Q

Type 2 and Gestational diabetes can be ____ or ___ controlled

A

Insulin or Diet

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14
Q

Risk Factors of Type 2 and Gestational diabetes

A
Polyhydramnios
excessive weight gain
macrocosmic infants shoulder dystocia
Nerve damage 
pre-clampsia
Fetal deaths
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15
Q

When is a maternal glucose screen performed?

A

24-28 weeks

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16
Q

What value of glucose is abnormal

testing for intolerance only

A

> 7.8 mmol/L

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17
Q

GCT test you’re given __mg of glucose and maternal blood is testes __ hours after

A

50; 1

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18
Q

GTT test you’re given __mg of glucose and maternal blood is testes __ hours after

A

100; 1, 2 & 3

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19
Q

When is a GTT (glucose tolerance test) warranted

A

if the GCT test (glucose challenge test) is over 7.8-11 mmol/L

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20
Q

What does it mean if the GCT test is >11.1 m mol/L

A

Gestational diabetes

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21
Q

Sonographic features in GDM

A

Extra views for LGA fetus

22
Q

Fetal subcutaneous fat measurement should be?

23
Q

Interventricular septum thickness should be?

24
Q

Hyperthyroidism (from graves disease) may cause: (3)

A

Goiter
Spontaneous abortion
congenital anomalies

25
With Hypothyroidism is rare in pregnancy as these people ...
cant conceive
26
What are 3 Hematologic Disorders?
1. Rh Isoimmunization - immunie hydrops 2. Sickle cell anemia 3. Heterozygous Thalassemia- hydrops
27
What test is done for maternal management of Hemolytic disease
Coombs Test
28
What are 2 types of Coombs tests
1. Direct | 2. Indirect
29
What is a Direct Coombs test?
not common detects antibodies that stuck to surface of RBC (fetus cord blood)
30
What is an indirect coobs test
detects antibodies that are free floating in the blood | more common and test is from the mother
31
What are Rh- mothers given an injection of?
RhD immune globulin
32
When are Rh- mothers given the injection?
28-32 weeks and again after delivery (within 72 hours)
33
What will the injection (RhoGAM or WINRho) prevent?
antibodies forming in the mother
34
Other reasons to administor WINrho in Rh- patients
``` Spontaneous abortion (72 hours) Therapeutic abortion Ectopic pregnancy After an AMNIOCENTESIS maternal hemorrhage, vaginal bleeding in pregnancy ``` (never give WINRho to a Rh+ mother)
35
A routine ___ and ___ is performed in fetal assessments with Rh disease
BPP; biometry
36
With Rh disease sonography assess for (3)
Anemia ascites (echogenic bowel) pleural and pericardial effusion
37
Doppler of the ___ is performed in Rh disease
MCA
38
A PSV of the MCA >__m/s = ____ in the fetus
1 ; severe anemia
39
MCA >1 m/s would require?
a blood transfusion
40
Phenylketonuria (PKU) is an...?
Inherited autosomal recessive disease
41
The diet provides this amino acid (Phenylketonuria) is acquired through ingestion of
protein (milk, eggs and some artificial sweeteners)
42
Women should follow a ___ Phenylketonuria diet
low. due to toxic levels of metabolic products
43
Phenylketonuria results in (6)
``` Microcephaly Mental retardation CHD Low birth rates Behavioural problems spontaneous abortion ```
44
What is a common infection in pregnancy
UTI's
45
What can UTI's cause
Pre-term labour
46
What can maternal obesity cause in mother?
Diabetes | Hypertension
47
What can maternal obesity have an increased incidence of in pregnancy
1 Multiples 2. UTIs 3. Uterine Fibroids (grow with estrogen)
48
What is excessive vomiting in pregnancy called?
Hyperemesis Gravidarum
49
What can Hyperemesis Gravidarum cause in mother
deyhydration | electrolyte imbalance
50
What is sonography used to rule out with Hyperemesis Gravidarum
TWINS | Trophoblasic disease
51
What is LUPUS
Systemic autoimmune disease that occurs when your body's immune system attacks your own tissues and organs.