[5] Pediatric Oncology Flashcards Preview

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Flashcards in [5] Pediatric Oncology Deck (43)
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1

What is the incidence of malignancies occurring in children?

1%

2

Define: Trismus

Inability to open mouth

3

Most common childhood cancer worldwide

Acute Lymphoblastic Leukemia

4

"True" 2nd most common cancer in children

Solid Tumor Brain Cancer (Medulloblastoma)

5

Children with Down Syndrome have an increased risk for developing this kind of cancer

Acute Myelogenous Leukemia

6

Children with Beckwith Wiedemann Syndrome have an increased risk for developing this kind of cancer

Hepatoblastoma
Wilm's Tumor

7

Red Flag indicator for Leukemia in a CBC

Very high lymphocyte count
Very low hemoglobin and platelets

8

If an ALL spreads to the chest, does this have a better or worse prognosis than if it spread to the abdomen?

If has a worse prognosis because it indicates an origin from the Thymus affecting T-cells, aBdominal spread indicates B-cell affectation and better prognosis

9

Test to differentiate between T and B cell Leukemia

Flow Cytometry (X-Ray can be used if funding is an issue, mediastinal node involvement is more likely T-Cell)

10

ALL Blast Cell Sanctuary Sties

Brain
Testicle

11

A fever of malignancy can be given this drug to check if it is indeed a malignancy

Naproxen

If the fever goes away immediately, it is most probably a malignancy

12

Peak ages of Hodgkin's Lymphoma

1st Peak: Adolescence
2nd Peak: 50-60 y/o

13

Hodgkin's Lymphoma is more common in males/females?

Males

14

This cancer is the most frequent cause of intussusception in children >6 years old

Non-Hodgkin's Lymphoma

15

Usual location of brain tumors in children >8 y/o

Supretentorial

16

Usual location of brain tumors in children

Infratentorial

17

2nd most common solid tumor in children

Neuroblastoma

18

Most common location of a neuroblastoma

Abdominal presentation

19

Most common pediatric malignancy of the kidney

Wilms' Tumor

20

Peak Age at Diagnosis of Wilms' Tumor

2-3 Years

21

Why is Thrombocytosis common in Hepatoblastoma Patients?

Results from production of cytokine members including TPO (Thrombopoietin), within tumor tissues

22

Most common liver tumor of childhood

Hepatoblastoma

23

First sign of Retinoblastoma

Leukocoria

24

Classic Radiologic Finding in Langerhans Cell Histiocytosis

Lytic Bone Lesion (Face or Base of Skull)

25

A 2-year-old male with macroglossia and RUQ mass
a. Leukemia
b. Hepatoblastoma
c. Non-Hodgkin Lymphoma
d. Neuroblastoma

B

26

3 year old female with 2 week history of ataxia and diplopia. Midline cerebellar mass on MRI
a. Leukemia
b. Wilm’s Tumor
c. Medulloblastoma
d. Retinoblastoma

C

27

Best treatment option for Acute Leukemia
a. Chemotherapy
b. Surgery
c. Radiation
d. Chemotherapy and Surgery

A

28

A patient with Leukocoria, OD, of 4 mos duration, presents to the ophtha clinic. There is a family history of eye tumors, but specific dx unrecalled. This is most likely?
a. Medulloblastoma
b. Astrocytoma
c. Orbital sarcoma
d. Retinoblastoma

D

29

Which of the ff would most likely present as an
asymptomatic abdominal mass?
a. Neuroblastoma
b. Hepatoblastoma
c. Wilms
d. Retinoblastoma

C

30

Neuroblastoma occurs
a. Only in the abdomen
b. Anywhere along the sympathetic chain
c. Anywhere along the spinal column

B