Lipid transporters

Question 1

Main lipid in chylomicrons

Answer 1

TAGs

Question 2

Apoproteins in chylomicrons

Answer 2

B-48 (A, C, and E)

Question 3

Function of chylomicrons

Answer 3

Transports dietary TAGs to adipose and other tissues

Question 4

Main lipid in chylomicron remnants

Answer 4

TAGs

Question 5

Apoproteins in chylomicron remnants

Answer 5

B-48 (A, C, and E)

Question 6

Function of chylmicron remants

Answer 6

Delivers remaining dietary TAGs to the liver; exchanges TAGs for CE and delivers CE to the liver

Question 7

Main lipid in VLDL

Answer 7

TAG

Question 8

Apoproteins in VLDL

Answer 8

B-100 (A, C, and E)

Question 9

Function of VLDL

Answer 9

• Transports endogenously synthesized TAGs to heart tissue, skeletal muscle, and adipose
• Exchanges TAGs for CE in HDLs

Question 10

What is IDL?

Answer 10

Remnants of VLDL after exchange with HDLs

Question 11

Main lipid in IDL

Answer 11

Cholesterol and TAGs

Question 12

Apoproteins in IDL

Answer 12

B-100 and E

Question 13

Function of IDL

Answer 13

Transports remaining TAG and traded CE to the liver

Question 14

How are LDLs formed?

Answer 14

Through processing of IDL on the way back to the liver

Question 15

Main lipid in LDLs

Answer 15

Cholesterol

Question 16

Apoproteins in LDLs

Answer 16

B-100

Question 17

Function of LDLs

Answer 17

Delivers cholesterol to the liver and other cells, including steroidogenic cells

Question 18

Where are HDLs formed?

Answer 18

In the liver, some in the intestines

Question 19

Main lipid in HDLs

Answer 19

Cholesterol

Question 20

Apoproteins in HDLs

Answer 20

A’s (C, E)

Question 21

Function of HDL

Answer 21

• Accepts cholesterol from peripheral cells, esterifies them, and transports them back to the liver
• Atheroprotective via enzymes such as paraoxonase that inhibits LDL oxidation
• Serves as a transporter for circulating lipoproteins