Calcium Chloride 10%

Question 1

Trade name

Answer 1

Calcium Chloride

Question 2

Class

Answer 2

Electrolyte

Question 3

Mechanism of Action

Answer 3

Increases cardiac contractile state (positive inotropic effect)

Question 4

Indications

Answer 4

Acute hyperkalemia (elevated potassium), acute hypocalcemia (decreased Calcium), Calcium channel blocker (nifedipine, verapamil, etc.)

Question 5

Contraindications

Answer 5

Current digoxin therapy; Hypercalcemia; Hypersensitivity

Question 6

Adverse effects

Answer 6

Bradycardia/ asystole arrest, hypotension, severe tissue necrosis if the is solution extravasation

Question 7

Incompatabilitie/ Drug interactions

Answer 7

all drugs - flush line before adminstration

Question 8

Routs of administration

Answer 8

Slow IV/IO over 2-3 minutes, ECG monitor recommended.

Question 9

Onset of action

Answer 9

Within seconds; peak effect 3-5 minutes; duration of 15-30 minutes

Question 10

Adult dose

Answer 10

Hypocalcemia, calcium channel blocker OD, hyperkalemia and hypermagnesemia -
Calcium Choride 10% 10ml slow IV/IO over 2-3 minutes
Flush line before admin
May repeat in 10 min

Pretreat for IV/IO calcium channel blocker administration
300mg slow IV/IO
May repeat once

Question 11

Pediatric dose

Answer 11

Hypocalcemia, calcium channel blocker OD, hyperkalemia and hypermagnesemia

Calcium Chloride 10% 20mg/kg slow IV/IO over 2-3 min
Repeat in 10 min if clinical indication persists (calcium channel blocker OD)
Max 1gm dose

Question 12

Special considerations

Answer 12

Calcium Chloride is not recommended in patients with suspected digitalis toxicity

Use of smaller doses with patients taking Digitoxin, due to it possibly causing cardiac irritability

Rapid administration may cause bradycardia and hypotension; monitor blood pressure, heart rate and EKG

Question 13

Protocols used

Answer 13

A-8 Asystole/PEA
A-22 Overdose
A-26 Special considerations in renal PTS
C-7 Acute Crush injuries