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PAtho > Unit 11 > Flashcards

Unit 11 Flashcards

1
Q

lung ca

A

rt death by disease, mostly avoidable

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2
Q

mortality of lung ca

A

30%

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3
Q

characteristics of lung c

A

aggressive, invasive, metastic

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4
Q

where does lung c met to

A

brain, bones ,liver

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5
Q

4 primary types of lung ca

A

adenocarcinoma
squamous cell carcinoma
large cell carcinoma
small cell carcinoma

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6
Q

2 cats of primary lung ca

A

1 - not small cell lung ca

2 - small cell lung ca

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7
Q

what ca’s are in nsclc

A

adenocaracino
squamous cell carcinoma
large cell carcinoma

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8
Q

what cas are in sclc

A

small cell carcinoma

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9
Q

what is the 5th type of primary lung ca

A

mixed group

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10
Q

what percent of lug ca is adenocarcinoma

A

30

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11
Q

what percent of lung ca is squamous cell carcinoma

A

30

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12
Q

what percent of lung ca is large cell carcinoma

A

12

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13
Q

what percent of lung ca is small cell carcinoma

A

22

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14
Q

et of lung ca

A

smoking (80)
toxins (eg asbestos)
genetic predisposition

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15
Q

where does 95% of lung ca originate

A

bronchi

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16
Q

where does squamous cell carcinoma originate

A

hilum of central bronchi

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17
Q

where does squamous cell carcinoma spread

A

regionally to hilar nodes

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18
Q

who has increased dispostion to squamous cell carcinoma

A

men

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19
Q

what may tumor spread of squamous cell carcinoma cause

A

impact to pericardium -> dec heart fx

20
Q

where does adenocarcinoma originate

A

peripherary

21
Q

what is adenocarcinoma assoc with

A

alveoli and bronchioles

22
Q

who has an increase in adenocarcinoma

A

women, non smokers

23
Q

where does large cell carcinoma originate

A

peripheray

24
Q

characteristics of large cell carcinoma

A

large, undifferentiated cells

mets early

25
Q

which ca out of all nsclc has poorest prognisis

A

large cell carcinoma

26
Q

characteristic of cells in small cell carcinoma

A

small, oval, oat like cells

27
Q

which population experiences an increase in small cell carcinoma

A

99% smokers

28
Q

characteristics of small cell carcinoma

A

aggressive, invasive with slim prognosis

29
Q

where does small cell carcinoma met to early

A

brain

30
Q

what percent of small cell carcinoma has mets at dx

A

70

31
Q

what does small cell carcinoma do to local tissue

A

invades quickly

32
Q

what is said about excision of small cell carcinoma

A

hard to excise, not resectable, cells may not be massed together

33
Q

what tx does small cell carincoma have inc response to

A

radiation, said to be radiosensitive

34
Q

what is a commone SE of small cell carcinoma

A

paraneoplastic syndrome

35
Q

what conditions are included in paraneoplastic syndrome

A

SIADH (adh)

cushings (cortisol, adrenocortico)

36
Q

what are mnfts of all lung ca’s based on

A

type, site, ext of local invasion, mets

37
Q

central mnfts of lung ca

A

large aw obst, impaired breathing, unexplained coughing, wheezing, dyspnea

38
Q

other mnfts of lung ca

A

paraneoplastic syndrome
hemoptysis
pain
cardiac mnfts

39
Q

hemoptysis

A

coughing blood rt vessel damage caused by malignancy

40
Q

cardiac mnfts in lung ca

A

rt inc P on heart. tumor has to affect pericardium, central malignancy only

41
Q

dx for lung ca

A 
hx, px
rule out URT, CLD
cxr, CT, US, MRI
bronchophy/needle biopsy
sputum analysis/ bronchiol wash
42
Q

what is tx for lung ca basedo n

A

type

43
Q

tx for nsclc

A

sx, radiation, chemo

44
Q

tx for sclc

A

chemo radiation

45
Q

why does lung ca have poor prognosis

A

no good screen -> dec detection

PAtho (31 decks)

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