5.1 Flashcards

(49 cards)

1
Q

what score is used to diagnose hirsutism

A

ferriman-gallwey (>8)

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2
Q

btwn LH and FSH, which is higher in PCOS

A

LH (3:1)

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3
Q

what will you see on PE for PCOS

A

bilateral enlarged smooth and mobile ovaries

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4
Q

what criteria is used to diagnose PCOS

A

Rotterdam criteria (2 out of 3)

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5
Q

what are the Rotterdam criteria

A

Hyperandrogenism
Oligomenorrhea/Amenorrhea
Cysts on US

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6
Q

are prolactinomas usually benign or malignant

A

benign

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7
Q

MC pituitary adenoma

A

prolactinoma

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8
Q

prolactinomas are associated with what inherited disease

A

MEN1

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9
Q

what inhibits prolactin release

A

dopamine

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10
Q

effects of prolactinoma on growth

A

acromegaly in adults
gigantism in kids

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11
Q

common prolactinoma sx in women

A

galactorrhea
amenorrhea/oligorrhea
decreased vaginal lubrication

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12
Q

local compression from prolactinoma can cause

A

visual changes (bitemporal hemianopsia)
headache

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13
Q

FSH and LH in prolactinoma

A

decreased

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14
Q

what imaging for prolactinoma

A

MRI

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15
Q

tx for prolactinoma

A

dopamine agonists (Bromocriptine, Cabergoline)

Transsphenoidal surgery

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16
Q

what is a good marker for progress in ovarian CA

A

CA125

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17
Q

what type of ovarian cyst is low risk for CA

A

fluid filled, anechoic

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18
Q

what type of ovarian cyst is high risk for CA

A

nodular, solid

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19
Q

closed comedomes

A

whiteheads

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20
Q

open comedomes

21
Q

what gland is NOT affected in Sheehan’s syndrome

A

posterior pituitary

only one that is affected in anterior pituitary

22
Q

common sx of Sheehan’s

A

agalactorrhea
amenorrhea
hypoTN
tachycardia
hyponatremia

23
Q

what will you see on MRI for sheehan

A

pituitary ring sign

24
Q

primary adrenocortical insufficiency (Addison’s dz)

A

decreased cortisol
decreased aldosterone
elevated ACTH

25
tx for primary adrenocortical insufficiency
glucocorticoids mineralocorticoids can be added ONLY for primary (bc we have decreased aldosterone only in primary)
26
secondary adrenocortical insufficinecy (issue w pituitary)
decreased cortisol intact aldosterone decreased ACTH
27
deficiency in aldosterone (most prominent in primary adrenocortical insufficiency) most commonly leads to
orthostatic hypoTN
28
MC cause of addisonian crisis
rapid withdrawal of glucocorticoids
29
Cushing syndrome
excess cortisol (main)
30
high dose Dexamethasone suprpession test (Cushings) for Cushing's disease (pituitary adenoma --> ACTH)
increased ACTH + suppression of cortisol with high-dose dexamethasone
31
high dose Dexamethasone suprpession test (Cushings) for ectopic tumor (like small cell lung CA producing ACTH)
increased ACTH + no suppression of cortisol with high dose
32
high dose Dexamethasone suppression test (Cushing's) for adrenal tumor
decreased ACTH + increased cortisol/no suppression of cortisol
33
tx for cushings
corticoid steroid TAPER
34
if we have hypotension with adrenocortical insufficiency, what will we have with Cushing's syndrome
HTN
35
ATP 3 criteria (3 of the following) for metabolic syndrome
HDL < 40 in men; < 50 in women Increased BP >/= 135 S or >/=85 D or drug tx Increased TG >/=150 or tx Increased fasting blood sugar >/= 100 or tx Increased waist circumference 40 in men and 35 in women (inches)
36
what rash is associated w celiac disease
dermatitis herpetiformis
37
everyone w PCOS should be tested for
NCAH
38
17-hydroxyprogesterone measurements for NCAH
> 1000 -- likely < 200 -- unlikely (rule out)
39
what type of amenorrhea do people with anorexia have
hypogonadotropic hypogonadism
40
Turner's syndrome - primary labs
low estrogen high FSH, high LH
41
Klinefelter's syndrome - primary labs
low testosterone high FSH, high LH
42
first line for ovulation induction in PCOS
Letrozole can also do Clomiphene
43
testosterone levels for when to suspect adrenal secreting tumor
> 150
44
A1C levels for normal, pre diabetes, diabetes
normal < 5.7 pre diabetes 5.7-6.4 diabetes > 6.5
45
A PCOS phenotype
full; amenorrhea/oligorrhea, hyperandrogens, cysts
46
B PCOS phenotype
classic amenorrhea/oligorrhea, hyperandrogens
47
C PCOS phenotype
hyperandrogens and cysts
48
D PCOS phenotype
cysts and oligo/amenorrhea
49
BMI index
< 18.5 underweight 18.5-24.9 normal 25-29.9 overweight 30-34.9 obese > 35 morbidly obese