Topic 6.1: Digestion and Absorption Flashcards

1
Q

What are two major groups of organs which comprise the human digestive system?

A

alimetary canal and accessory organs

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2
Q

Define alimentary canal

A

The alimentary canal consists of organs through which food actually passes (oesophagus, stomach, small & large intestine)

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3
Q

Define accessory organs

A

The accessory organs aid in digestion but do not actually transfer food (salivary glands, pancreas, liver, gall bladder)

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4
Q

Is the esophagus part of the alimetary canal or accessory organs?

A

alimetary canal

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5
Q

Is the stomach part of the alimetary canal or accessory organs?

A

alimetary canal

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6
Q

Is the small intestine part of the alimetary canal or accessory organs?

A

alimetary canal

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7
Q

Is the salivary glands part of the alimetary canal or accessory organs?

A

accessory organs

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8
Q

Is the pancreas part of the alimetary canal or accessory organs?

A

accessory organs

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9
Q

Is the liver part of the alimetary canal or accessory organs?

A

accessory organs

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10
Q

Is the gall bladder part of the alimetary canal or accessory organs?

A

accessory organs

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11
Q

Is the large intestine part of the alimetary canal or accessory organs?

A

alimetary canal

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12
Q

What is the structure and function of the oesophagus?

A

A hollow tube connecting the oral cavity to the stomach (separated from the trachea by the epiglottis)

• Food is mixed with saliva and then is moved in a bolus via the action of peristalsis

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13
Q

What is the structure and function of the stomach?

A

A temporary storage tank where food is mixed by churning and protein digestion begins

• It is lined by gastric pits that release digestive juices, which create an acidic environment (pH ~2)

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14
Q

What is the structure and function of the small intestine?

A

A long, highly folded tube where usable food substances (nutrients) are absorbed

• Consists of three sections – the duodenum, jejunum and ileum

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15
Q

What is the structure and function of the large intestine?

A

The final section of the alimentary canal, where water and dissolved minerals (i.e. ions) are absorbed

• Consists of the ascending / transverse / descending / sigmoidal colon, as well as the rectum

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16
Q

What is the structure and function of the salivary glands?

A

Release saliva to moisten food and contains enzymes (e.g. amylase) to initiate starch breakdown

• Salivary glands include the parotid gland, submandibular gland and sublingual gland

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17
Q

What is the structure and function of the pancreas?

A

Produces a broad spectrum of enzymes that are released into the small intestine via the duodenum

• Also secretes certain hormones (insulin, glucagon), which regulate blood sugar concentrations

18
Q

What is the structure and function of the liver?

A

Takes the raw materials absorbed by the small intestine and uses them to make key chemicals

• Its role includes detoxification, storage, metabolism, bile production and haemoglobin breakdown

19
Q

What is the structure and function of the gall bladder?

A

The gall bladder stores the bile produced by the liver (bile salts are used to emulsify fats)

• Bile stored in the gall bladder is released into the small intestine via the common bile duct

20
Q

What is the first step of mechanical digestion?

A

Food is initially broken down in the mouth by the grinding action of teeth (chewing or mastication)

21
Q

After Food is initially broken down in the mouth by the grinding action of teeth (chewing or mastication), what is the next step of mechanical digestion?

A

The tongue pushes the food towards the back of the throat, where it travels down the esophagus as a bolus

22
Q

After The tongue pushes the food towards the back of the throat, where it travels down the esophagus as a bolus, what is the next step of mechanical digestion?

A

The epiglottis prevents the bolus from entering the trachea, while the uvula prevents the bolus from entering the nasal cavity

23
Q

After The epiglottis prevents the bolus from entering the trachea, while the uvula prevents the bolus from entering the nasal cavity, what is the next step of mechanical digestion?

A

The stomach lining contains muscles which physically squeeze and mix the food with strong digestive juices (‘churning’)

24
Q

After The stomach lining contains muscles which physically squeeze and mix the food with strong digestive juices (‘churning’), what is the next step of mechanical digestion?

A

Food is digested within the stomach for several hours and is turned into a creamy paste called chyme

25
Q

After Food is digested within the stomach for several hours and is turned into a creamy paste called chyme, what is the next step of mechanical digestion?

A

Eventually the chyme enters the small intestine (duodenum) where absorption will occur

26
Q

After Eventually the chyme enters the small intestine (duodenum) where absorption will occur, what is the last step of mechanical digestion?

A

Segmentation contractions move chyme in both directions, allowing for a greater mixing of food with digestive juices

27
Q

What is segmentation (digestion)?

A

Segmentation involves the contraction and relaxation of non-adjacent segments of circular smooth muscle in the intestines

28
Q

What is the first step of chemical digestion?

A

The stomach contains gastric glands which release digestive acids to create a low pH environment (pH ~2)

29
Q

After The stomach contains gastric glands which release digestive acids to create a low pH environment (pH ~2), what is the next step of chemical digestion?

A

The acidic environment functions to denature proteins and other macromolecules, aiding in their overall digestion

30
Q

After The acidic environment functions to denature proteins and other macromolecules, aiding in their overall digestion, what is the next step of chemical digestion?

A

The stomach epithelium contains a mucous membrane which prevents the acids from damaging the gastric lining

31
Q

After The stomach epithelium contains a mucous membrane which prevents the acids from damaging the gastric lining, what is the next step of chemical digestion?

A

The pancreas releases alkaline compounds (e.g. bicarbonate ions), which neutralise the acids as they enter the intestine

32
Q

After The pancreas releases alkaline compounds (e.g. bicarbonate ions), which neutralise the acids as they enter the intestine , what is the next step of chemical digestion?

A

The liver produces a fluid called bile which is stored and concentrated within the gall bladder prior to release into the intestine

33
Q

After The liver produces a fluid called bile which is stored and concentrated within the gall bladder prior to release into the intestine, what is the next step of chemical digestion?

A

Bile contains bile salts which interact with fat globules and divide them into smaller droplets (emulsification)

34
Q

After Bile contains bile salts which interact with fat globules and divide them into smaller droplets (emulsification), what is the next step of chemical digestion?

A

The emulsification of fats increases the total surface area available for enzyme activity (lipase)

35
Q

After The emulsification of fats increases the total surface area available for enzyme activity (lipase), what is the last step of chemical digestion?

A

Enzymes are biological catalysts which speed up the rate of a chemical reaction (i.e. digestion) by lowering activation energy
Enzymes allow digestive processes to therefore occur at body temperatures and at sufficient speeds for survival requirements
Enzymes are specific for a substrate and so can allow digestion of certain molecules to occur independently in distinct locations

36
Q

What are the four main tissue layers of the small intestine from outside to center?

A

serosa, muscle layer, submucosa, mucosa

37
Q

Define serosa (small intestine)

A

Serosa – a protective outer covering composed of a layer of cells reinforced by fibrous connective tissue

38
Q

Define muscle layer (small intestine)

A

Muscle layer – outer layer of longitudinal muscle (peristalsis) and inner layer of circular muscle (segmentation)

39
Q

Define submucosa (small intestine)

A

Submucosa – composed of connective tissue separating the muscle layer from the innermost mucosa

40
Q

Define mucosa (small intestine)

A

Mucosa – a highly folded inner layer which absorbs material through its surface epithelium from the intestinal lumen

41
Q

What is the function of villi in the small intestine?

A

Villi increase the surface area of epithelium over which absorption is carried out

• Villi absorb monomers formed by digestion as well as mineral ions and vitamins