S. aureus

Question 1

a-type phenol soluble modulins

Answer 1

They are able to kill neutrophils through a receptor independent process. They form pores

Question 2

LukGH

Answer 2

Lyse cells ; pore forming ; neutrophils

Question 3

Panton Valentine

Answer 3

Another luekocidin; can lyse neutrophils through pore formation

Question 4

CHIPS

Answer 4

Stands for chemotaxis inhibitory protein. It’s mode of action is that it binds C5aR and the formyl peptide receptor.

Question 5

FLIPr

Answer 5

binds to formyl peptide receptors

Question 6

Staphylokinase

Answer 6

Has the ability to cleave C3b, therefore inhibiting complement.

Question 7

Protein A

Answer 7

Binds to antibodies non-specifically. This prevents it from becoming phagocytosed

Question 8

Capsule formation

Answer 8

Capsules make the bacteria more slippery, making becoming phagocytozed more difficult.

Question 9

Catalase

Answer 9

inhibits ROS

Question 10

Superoxide dismutase

Answer 10

inhibits ROS

Question 11

Staphyloxanthin

Answer 11

inhibits ROS. it’s the gold pigment of S aureus.