Glaucoma Treatment and Practice Problems

Question 1

Which type of drugs are contraindicated in closed angle glaucoma?

Answer 1

Antimuscarinic

Alfa-1 agonists

Question 2

Mechanism of action of latanoprost

Answer 2

Prostaglandin analog (PGF2alfa)
⬆️ outflow of aqueous humor ▶️ ⬇️ Intraocular pressure

Question 3

Selective B2 agonist

Answer 3

Salmeterol, terbutaline, alboterol

Question 4

If ask by a beta-1=beta-2 blockade what compounds you may think?

Answer 4

Isoproterenol

Low dose epinephrine

Question 5

Why an acetylcholinesterase inhibitor doesn’t vasodilate?

Answer 5

⬆️ Ach in nerve terminals but there is no parasympathetic innervation on blood vessels (just M3 not innervated)