Week 6 - Nervines Flashcards

1
Q

Nervine

A
  • Term that broadly defines a category of botanical medicines that act on the nervous system
  • Can be further divided into nerve tonics, sedatives, and hypnotics
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2
Q

Nerve Tonic

A
  • Substance that improves the tone and vigor or function of the nervous system
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3
Q

Sedative

A
  • Also called relaxant
  • Decrease stimulation to the nervous system
  • Overall effect is calming
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4
Q

Hypnotic

A
  • Often stronger than sedatives
  • Cause drowsiness
  • May alter mental status
  • Often have anodyne effects
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5
Q

Indications for Nervines

A
  • Anxiety
  • Depression
  • Exhaustion
  • Shock/trauma
  • Stress modulation
  • Pain modulation
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6
Q

Nervines

A
  • Avena sativum (Milky Oat Seed)
  • Scutellaria lateriflora (Skullcap)
  • Humulus lupulus (Hops)
  • Valeriana officinalis (Valerian)
  • Piper methysticum (Kava)
  • Melissa officinalis (Lemon Balm)
  • Leonurus cardiaca (Motherwort)
  • Hypericum perforatum (St. John’s Wort)
  • Passiflora incarnata (Passion Flower)
  • Matricaria recutita (Chamomile)
  • Eschscholtzia californica (California Poppy)
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7
Q

Avena sativa - Family

A
  • Poaceae
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8
Q

Avena sativa - Parts Used

A
  • Immature milky seed
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9
Q

Avena sativa - Energetics

A
  • Moistening
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10
Q

Avena sativa - Indications

A
  • Nervous exhaustion
  • Nervous headache
  • Cardiac weakness due to nervous depression or debility
  • Opiate withdrawal
  • Nicotine withdrawal
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11
Q

Avena sativa - Contraindications

A
  • May diminish effect of opiates
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12
Q

Avena sativa - Other

A
  • Trophorestorative of nervous system

- In “kick juice” formula to stop smoking

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13
Q

Scutellaria lateriflora - Family

A
  • Lamiaceae
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14
Q

Scutellaria lateriflora - Parts Used

A
  • Aerial parts in bloom
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15
Q

Scutellaria lateriflora - Energetics

A
  • Cooling
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16
Q

Scutellaria lateriflora - Indications

A
  • Insomnia
  • Restlessness
  • Anxiety
  • Agitation
  • Teething
  • Headache from exhaustion
  • Chorea
  • Seizures
  • Neuralgia
  • Muscular fasciculations
  • Exhaustion due to illness
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17
Q

Scutellaria lateriflora - Contraindications

A
  • May potentiate the effects of other sedative medications
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18
Q

Scutellaria lateriflora - Other

A
  • Gentle
  • Very effective
  • Great for kids
  • Some consider it trophorestorative of nervous system
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19
Q

Humulus lupulus - Family

A
  • Cannabaceae
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20
Q

Humulus lupulus - Parts Used

A
  • Strobile (its flowering body; like soft pinecones)
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21
Q

Humulus lupulus - Energetics

A
  • Cooling

- Lax

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22
Q

Humulus lupulus - Indications

A
  • Delirium tremens (alcohol withdrawal)
  • Restless leg syndrome
  • Dyspepsia
  • Nervous headache
  • Generalized nervous tension
  • Insomnia
  • Increase lactation
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23
Q

Humulus lupulus - Contraindications

A
  • Depression

- Pregnancy

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24
Q

Humulus lupulus - Other

A
  • Can be put into a pillow

- Non-alcoholic beer study for sleep in stressed population

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25
Q

Valeriana officinalis - Family

A
  • Valerianaceae
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26
Q

Valeriana officinalis - Part Used

A
  • Root
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27
Q

Valeriana officinalis - Energetics

A
  • Warming

- Lax

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28
Q

Valeriana officinalis - Indications

A
  • Sleeping formulas
  • Musculoskeletal formulas
  • General relaxation
  • Nervousness
  • Mental depression and despondency
  • Hysteria and hypochondria
  • Nervous headache
  • Hemicrania
  • Chorea
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29
Q

Valeriana officinalis - Contraindications

A
  • May potentiate the actions of other sleep-inducing agents
  • Long-term use was associated with benzodiazepine-like withdrawal in rats due to GABA receptor activity (one case of life-threatening withdrawal syndrome after surgery)
30
Q

Valeriana officinalis - Other

A
  • Wean off slowly
  • 10-15% has an opposite reaction (alert, awake)
  • Increases GABA, which decreases CNS excitation
  • Decreases BP through vasodilation and smooth muscle relaxation
  • Decreases wakefulness without causing morning hangover
  • Helpful in benzodiazepine withdrawal
  • Specifically indicated in mental depression with nervousness
  • Has synergistic action with cimicifuga
  • Proven effective in OCD study
  • Proven useful in preventing postoperative cognitive dysfunction after CABG surgery
  • Neuroprotective
31
Q

Piper methysticum - Family

A
  • Piperaceae
32
Q

Piper methysticum - Part Used

A
  • Roots
33
Q

Piper methysticum - Energetics

A
  • Warming
34
Q

Piper methysticum - Indications

A
  • Anxiety
  • Insomnia
  • Fibromyalgia
  • Cholecystitis
  • Ureteral spasm
  • Interstitial cystitis
  • Tension headache
  • Neuralgia
  • Kidney stones
35
Q

Piper methysiticum - Contraindications/Cautions

A
  • Pregnancy
  • Lactation
  • Liver disease
  • Potentiates the effects of alcohol
  • Benzodiazepines
  • Can be toxic!
36
Q

Piper methysticum - Other

A
  • Can be toxic!
  • Has a very immediate effect (use mostly for in-the-moment anxiety)
  • Native to Pacific Islands
  • Some people are more sensitive to it, so need to watch for ssx of liver disease
  • Long-term use has higher incidence of hepatotoxicity
  • Potential inhibition of cytochrome P450
37
Q

Melissa officinalis - Family

A
  • Lamiaceae
38
Q

Melissa officinalis - Parts Used

A
  • Whole plant before flowering
39
Q

Melissa officinalis - Energestics

A
  • Uplifting

- Cooling

40
Q

Melissa officinalis - Indications

A
  • Nervous dyspepsia
  • Anxiety
  • Depression
  • Insomnia
  • Migraines (particularly where stress is the cause)
  • Hyperthyroidism
  • Herpes simplex (used topically)
41
Q

Melissa officinalis - Contraindications

A
  • Hypothyroidism

- Pregnancy

42
Q

Melissa officinalis - Other

A
  • Called the “gladdening herb”
  • Powerful antioxidant effects due to rosmarinic acid
  • Inhibits TSH binding to TSH receptors
  • Inhibits GABA transaminase
  • Improved mental performance in mild/moderate Alzheimer patients
  • Improvement in oxidative stress and DNA damage in radiology staff
  • Neuroprotective
  • Gentle, effective
  • Anti-inflammatory, antioxidant
  • Increases processing speed
43
Q

Leonurus cardiaca - Family

A
  • Lamiacea
44
Q

Leonurus cardiaca - Parts Used

A
  • Aerial parts
45
Q

Leonurus cardiaca - Energetics

A
  • Neutral

- Drying

46
Q

Leonurus cardiaca - Indications

A
  • Nervousness
  • Irritability
  • Palpitations
  • Hyperthyroidism (and look-alike sx)
  • Amenorrhea
  • Postpartum depression
47
Q

Leonurus cardiaca - Contraindications/Cautions

A
  • Pregnancy
  • Doses over 3g may cause diarrhea, uterine bleeding, or GI upset
  • Hypothyroidism
48
Q

Leonurus cardiaca - Other

A
  • “Motherwort is tonic and laxative, a diaphoretic somewhat like asclepias (pleurisy root), an emmenagogue like cimicifuga, and a nervine like scutellaria”
49
Q

Hypericum perforatum - Family

A
  • Hypericaceae
50
Q

Hypericum perforatum - Parts Used

A
  • Fresh aerial parts
51
Q

Hypericum perforatum - Energetics

A
  • Mildly warming

- Enlightening

52
Q

Hypericum perforatum - Indications

A
  • Wound healing
  • Mild/moderate depression
  • Neuralgia
  • Nerve injury
  • Burns (topical)
53
Q

Hypericum perforatum - Contraindications

A
  • Induces CYP 3A4 and can cause increased clearance of pharmaceutical drugs (caution with all drugs - check for herb/drug interactions)
54
Q

Hypericum perforatum - Other

A
  • Synergistic in formulas for pain
  • Often gets sprayed, so harvest with caution
  • Very low toxicity
  • Can cause phototoxicity in large doses
  • Antiviral and antiretroviral activity
55
Q

Passiflora incarnata - Family

A
  • Passifloraceae
56
Q

Passiflora incarnata - Parts Used

A
  • Whole plant
57
Q

Passiflora incarnata - Energetics

A
  • Cooling
58
Q

Passiflora incarnata - Indications

A
  • Anxiety
  • Nervous headache
  • Restlessness
  • Insomnia
59
Q

Passiflora incarnata - Contraindications

A
  • Pregnancy

- Potentiates sedative drugs

60
Q

Matricaria recutita - Family

A
  • Asteraceae
61
Q

Matricaria recutita - Parts Used

A
  • Flower
62
Q

Matricaria recutita - Energetics

A
  • Cooling
63
Q

Matricaria recutita - Indications

A
  • Nervousness
  • Impatience
  • Discontent
  • Insomnia
  • Particularly useful in children
64
Q

Matricaria recutita - Contraindications/Cautions

A
  • High doses can cause vomiting and diarrhea
65
Q

Matricaria recutita - Other

A
  • Only need to use low doses
  • Very good for kids
  • Can be added as an activator to formulas
66
Q

Eschscholtzia californica - Family

A
  • Papaveraceae
67
Q

Eschscholtzia californica - Parts Used

A
  • Whole plant
68
Q

Eschscholtzia californica - Energetics

A
  • Cooling
69
Q

Eschscholtzia californica - Indications

A
  • Anxiety
  • Overexcitement
  • Restlessness
  • Insomnia
  • ADD/ADHD
70
Q

Eschscholtzia californica - Contraindications

A
  • Pregnancy
71
Q

Eschscholtzia californica - Other

A
  • In post-surgical pain formula
  • Happy and uplifting
  • Non-toxic and safe for kids
  • Non-addictive and no side effects