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Medicine SHELF Prep > Endocrine > Flashcards

Endocrine Flashcards

1
Q

Treatment of Central DI

A

Desmopressin

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2
Q

Dx of acromegaly

A

IGF-1

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3
Q

Tx of acromegaly

A

pituitary resection; octreotide/lanreotide adjuvantly

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4
Q

Which diagnosis? Low TSH and normal T4

A

Subclinical thyrotoxicosis

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5
Q

Indication for RAIU scan

A

Low TSH and High T4

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6
Q

Indication for checking thyroglobulin

A

Low TSH/High T4 and low/absent RAIU

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7
Q

Which diagnosis? hyperthyroid labs and low thyroglobulin

A

Factitious

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8
Q

Indication for thyroid nodule biopsy/FNA

A

> 1cm

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9
Q

Mx of thyroid storm (4)

A

propranolol, Methimazole/PTU, inorganic iodide, +/- steroids

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10
Q

Dx of primary adrenal insufficiency

A

Cosyntropin/ACTH stim test

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11
Q

Tx of acute primary adrenal insufficiency

A

High dose steroids and IVF

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12
Q

Screening for Cushing Syndrome (3)

A

Midnight salivary cortisol, 1mg Dexamethasone suppression test, 24 hour urine cortisol

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13
Q

Confirmatory testing for Cushing Syndrome

A

2mg dexamethasone suppression test

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14
Q

Next best test after confirming Cushing Syndrome

A

ACTH level

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15
Q

Screening for hyperaldosteronism

A

Aldosterone/Renin ratio

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16
Q

Confirmatory testing for hyperaldosteronism

A

Sodium challenge/Aldosterone suppression test

17
Q

Tx of hyperaldosteronism secondary to bilateral adrenal hyperplasia (2)

A

Aldosterone antagonist, dietary salt restriction

18
Q

Medical Mx of pheochromocytoma

A

Alpha blocker (phenoxybenzamine), then beta-blocker

19
Q

DM screening

A

BP >135/80, overweight with risk factors, all at age 45

20
Q

Which DM medication? decreases hepatic glucose production

A

Metformin

21
Q

Which DM medication? can cause hypoglycemia and weight gain

A

Sulfonylureas (glipizide, glyburide)

22
Q

Which DM medication? injectable, may help weight loss

A

GLP-1 agonist (exenatide, liraglutide)

23
Q

Which DM medication? weight neutral, may cause urticaria/angioedema

A

DPP-4 inhibitors (-gliptin)

24
Q

Which DM medication? may improve lipid profile, edema and heart failure risk, increased risk of bladder cancer

A

Thiazolidinediones (-glitazone)

25
Q

Which DM medication? flatulence abdominal discomfort

A

acarbose (other alpha-glucosidase inhibitors)

26
Q

Which DM medication? Increased risk of vulvovaginal candidiasis/UTI

A

SGLT2 inhibitors (-gliflozin)

27
Q

Indication for ACEI in diabetic nephropathy

A

Alb/Cr ratio >30mg/g

28
Q

Tx DKA- Insulin/fluids

A

0.15U/kg insulin bolus then 0.1U/kg/hr, NS switch to D5-1/2NS at glucose 200-250

29
Q

Target glucose reduction in DKA

A

50-100/hr

30
Q

HHS vs. DKA Mx

A

HHS 1L NS prior to insulin; 0.1U/kg bolus

31
Q

Target osmolality reduction in HHS

A

3mOsm/hr

32
Q

C/I to bisphosphonates

A

CKD

Medicine SHELF Prep (12 decks)

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