Onc Flashcards

1
Q

Lung Ca Screening Indications

A

Age 55-80, 30py hx (within past 15 yrs)

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2
Q

Lung Ca Screening Test

A

Low-Dose CT

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3
Q

Lung Ca Staging

A

CT Chest/Abd, PET-CT chest

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4
Q

Absolute indication for lung nodule biopsy

A

> 1.5cm

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5
Q

Which Lung Ca stage? Mediastinal involvement

A

III

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6
Q

Which Lung Ca stage? Ipsilateral node positive

A

II

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7
Q

Tx NSCLC Stage I-II

A

Surgery (adjuvant ctx for 1B+)

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8
Q

Tx NSCLC Stage III

A

Neoadjuvant Ctx, then surgery

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9
Q

Tx SCLC

A

Cisplatin + etoposide

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10
Q

Eval palpable lump under 30, more than 2 menstrual cycles

A

US

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11
Q

Eval palpable lump age over 30

A

Mammogram

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12
Q

Eval BIRADS 1-3

A

US

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13
Q

Eval BIRADS 4-5

A

Biopsy

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14
Q

Colorectal Ca Screening PSC

A

annual colonoscopy

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15
Q

Tx colorectal cancer: indications for chemotherapy

A

Stage III+ (node-positive)

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16
Q

Tx rectal cancer: indications for radiation therapy

A

Stage II+

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17
Q

Tx colorectal cancer regimen

A

5-FU + leucovorin + oxaliplatin

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18
Q

Cervical cancer staging

A

CT abd/pelvis, CXR

19
Q

Prostate Ca: indications for CT abd/pelvis and bone scan

A

PSA>10 or Gleason>7

20
Q

Tx prostate Ca hormone therapy

A

Leuprolide/goserelin + androgen inhibitor (flutamide or bicalutamide)

21
Q

Indication for melanoma SLNB

A

thickness >1mm

22
Q

Precursor lesion to melanoma

A

Dysplastic nevus

23
Q

Precursor lesion to squamous cell carcinoma (skin)

A

Actinic keratosis

24
Q

Indication for interferons in melanoma

A

Node-positive

25
Q

Dx Lymphoma

A

Excision lymph node biopsy

26
Q

Tx Hodgkin Lymphoma

A

ABVD: doxorubicin, bleomycin, vinblastine, dacarbazepine

27
Q

What testing is indicated in a patient with new dx of NHL?

A

HBV, HCV, HIV

28
Q

Which NHL type? MALT lymphoma

A

Marginal Zone

29
Q

Which NHL type? Cyclin D1 overexpression

A

Mantle Cell

30
Q

Which NHL type? c-myc, starry sky appearance

A

Burkitt

31
Q

Which NHL type? Most common

A

Diffuse Large B cell

32
Q

Which NHL type? Curable

A

Diffuse Large B cell, Burkitt

33
Q

Dx Chronic Lymphocytic Leukemia

A

Clonal >5,000 WBC increase in absence of cause

34
Q

Which sign/pathology? Onset of facial flushing and inspiratory stridor with raising arms above head

A

Pemberton sign/SVC syndrome

35
Q

Tx CNS metastases

A

Glucocorticoids

36
Q

Electrolyte disturbances in Tumor Lysis Syndrome (4)

A

Hypocalcemia, hyperkalemia, hyperphosphatemia, hyperuricemia

37
Q

Tx Hypercalcemia of Malignancy

A

NS/loop diuretics (+/- bisphosphonates)

38
Q

Which diagnosis? flushing, diarrhea, wheezing, pellagra

A

Carcinoid syndrome

39
Q

Which diagnosis? Palpitations, sweating, headache, confusion/seizures, hypoglycemia

A

Insulinoma

40
Q

Lung Ca associated with PTHrP

A

SCC

41
Q

Lung Ca associated with ACTH-secretion

A

SCLC

42
Q

Ca associated with Lambert-Eaton

A

SCLC

43
Q

Ca associated with DIC

A

APML

44
Q

Syndrome/Ca associated with clubbing and arthritis

A

Hypertrophic Pulmonary Osteoarthropathy/Lung carcinoma