5a Flashcards Preview

Ch 1-21 > 5a > Flashcards

Flashcards in 5a Deck (110)
Loading flashcards...
91

Phosphorous less that < 1 mg/dl leads to what

hemolysis, rhabdomyolysisMost dogs (other than Japanese or Koren--Akita, Shiba Inu, Kindo) have phosphorous independent RBC regulation and may NOT develop hemolysis

92

when does soft tissue mineralization occur with hyperP

Ca x P >> 60-70= soft tissue dystrophic mineralization

93

What is pseudo hyperchloridemia

automated analytical assays measure halides all under Cl(ex. KBr patient)

94

how are brain cells unique when it comes to glucose utilization

brain cells are permeable to glucosedo NOT require insulin to bring into cellsneuronal cells also don't synthesize their own glucose

95

hormones involved in glucose homeostasis

insulin--pancreatic B islet cellsglucagon--pancreatic alpha islet cellscortisolepinephrinegrowth hormone

96

liver role in glucose homeostasis

hypogly conditions:liver is stimulated via glucagon to make glucose (glycogenolysis, gluconeogensis)

97

How do glucometers work

need normal patient (not anemic)whole bloodAnemic patients or serum samples will read erroneously high

98

what is Whipple's triad

low BGclinical signs corresponding to low BGresolution of signs with glucose therapy

99

causes of hypoglycemia

1. excess insulin (iatrogenic, insulinoma, paraneoplastic, toxins-xylitol)2. increased glucose utilization (infection, exercise induced, paraneoplastic, pregnancy, polycythemia)3. decreased glucose production (liver fail, pediatric, toy breed, PSS, counter regulatory hormone deficiency, Addison

100

paraneoplastic hypoglycemia

hepatomashepatocellular carcinomas leimyomas/myosarcomas

101

Drugs/toxins that cause hypoglycemia

sulfonylureasbeta blockersinsulin overdosexylitol

102

tx hypoglycemia

dextrose bolus (0.5-1.0 g/kg) diluted 1:1 to prevent phlebitis(can worsen insulinomas)GCC, frequent meals

103

how common is stress induced hyperglycemia

16% critically ill dogs54% critically ill cats

104

discuss the mechanisms by which hyperglycemia has adverse effects on the body

1. osmotic force--can pull IC fluids out2. increased glucose goes into urine and osmotic diuresis occurs dehydrating patients 3. tissue damage (retinopathies, heart attacks, renal dz)

105

T/Fprogesterone causes hyperglycemia

TRUEP causes hyperglycemia during diestrus

106

in insulinoma patients ________administration may be more harmful and instead __________administration is used

dextrose is harmful because stimulates more insulinconsider glucagon CRI

107

what is the molecular weight of albumin and its half life

69,000 daltons16 hours

108

what is colloid oncotic pressure of plasma vs HES

plasma 25 mm HgHES 30 mm Hg

109

Aarnes et al AJVR 2009 administration of HES rather than LRS is recommended for treatment of isoflurane induced hypotension in dogs

TRUE

110

Gebhardt et al JVECCS 2009T/F there is a sign difference btwn non septic SIRS and sepsis survival rates in dogs base on initial C reactive protein concentrations

FALSE