6 Flashcards

(85 cards)

1
Q

Trazodone is a substrate of which CYP

A

CYP 3A4

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2
Q

are carbamazepine and depakote approved for bipolar depression in addition to mania?

A

no just acute mania

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3
Q

Somnambulism (sleep walking) and night terrors happens in which stage of sleep?

A

Stage IV (slow wave)

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4
Q

obesity rates higher in men or women?

A

women

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5
Q

conduction aphasia symptoms

A

repetition impaired
but relatively normal spontaneous speech

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6
Q

conduction aphasia lesion site

A

arcuate fasciculus - superior temporal or inferior parietal region

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7
Q

where is gabapentin excreted?

A

renally - no hepatic metabolism

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8
Q

which nerve innervates thumb, forefinger, and middle finger

A

median nerve

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9
Q

can carpal tunnel create pain up the arm to the shoulder?

A

yes - referred pain

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10
Q

most common anxiety disorder

A

specific phobia

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11
Q

clinical triad for NF-1

A

cafe au lait spots
neurofibromas
Lisch nodules

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12
Q

Does NF-1 or NF-2 lead to behavioral or cognitive impairments?

A

NF-1

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13
Q

inheritance pattern for NF-1 and NF-2

A

automosomal dominant

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14
Q

variable episodes of abdominal pain + psych symptoms with +fam hx

A

acute intermittent porphyria

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15
Q

most likely side effect of ipecac

A

cardiomyopathy, inc. QTc, valve insufficiency

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16
Q

Binswanger’s disease

A

AKA subcortical arterioscleotic encephalopathy

vascular dementia + gait d/o + pseudobulbar

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17
Q

which cognitive test helpful at diagnosing right hemispheric disease?

A

judgement of line orientation test (match lines of same slope)

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18
Q

which neuro dz is this - spontaneous crying or laughter, lability

A

psuedobulbar palsy

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19
Q

which neuro dz is this - worries or surprised appearance with opthalmoplegia, rigidity, dementia

A

progressive supranuclear palsy

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20
Q

treatment for cervical dystonia or blepharospasm

A

botox

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21
Q

rolandic epilepsy

A

benign childhood epilepsy - stops in adolescence, doesnt require treatment

somatosensory distubance of mouth, preserve consciousness

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22
Q

mucus in stool but no blood is with what disorder

A

IBS

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23
Q

inclusion body myositis versus polymyositis - which one affects more proximal versus distal muscles?

A

inclusion body - more distal muscles

polymyositis - more proximal muscles

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24
Q

tuberoinfundibular pathway goes from what to what

A

hypothalamus to pituitary

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25
nigrostriatal pathyway goes from what to what
substantia nigra to basal ganglia
26
mesolimbic pathway goes from what to what
ventral tegmental area to nucleus accumbens
27
most common mitochondrial disorder
mitochondrial encephalopathy lactic acidosis and stroke like episodes (MELAS)
28
botox MOA
blocks acetylcholine release from presynaptic vesicles
29
exclusions of tpa
major surgery in last 2 weeks signs of brain bleed BP>185/110
30
painless visual loss of one eye + white matter hyperintensities + vascular risk factors
anterior ischemic optic neuropathy (AION)
31
can alcohol, sedatives, and inhalants cause nystagmus?
yes
32
criteria for brain death
- apnea test - no breathing - absence of brain stem reflexes (ie. gagging, corneal) - isoelectric EEG - absence of cerebral blood flow - coma - no reversible causes
33
brisk deep tendon reflexes suggestive of upper or lower motor neuron dz?
upper
34
older person gets focal seizure. from what most likely?
GBM
35
which med can help with chorea in Huntington's?
haldol
36
triad of bacterial meningitis
fever, neck stiffness, headache
37
2 most common bacteria to cause meningitis
Strep pneumo, Neisseria meningitidus
38
most common pathogens for neonatal meningitis
Group B strep E coli Listeria
39
What does CSF look like for GBS?
elevated protein normal WBCs
40
cause of olfactory aura caused by seizures from what brain area
medial temporal lobe
41
cause of gustatory aura caused by seizures from what brain area
insula
42
lorazepam, oxazepam, temazepam metabolized by what
hepatic glucuronidation (versus oxidation)
43
CBC monitoring frequency of carbamazepine for agranulocytosis or aplastic anemia
every 3 months the first year, then can decrease frequency
44
is carbamazepine's side effects of agranulocytosis or aplastic anemia, steven johnson's syndrome, hepatic failure, pancreatitis dose dependent?
no
45
can you take both carbamazepine and clozapine?
no! risk of agranulocytosis
46
most common side effects of donepezil
GI - nausea, abdominal cramping
47
clostridium tetani causes spasms and rigidty by
inhibiting release of GABA and glycine (inhibitory NTs) in brain stem and spinal cord --> contractions
48
which stage of sleep has sleep spindles and K complexes?
N2
49
which stage of sleep has slowing of alpha activity?
N1
50
which stage of sleep has slow wave delta?
N3
51
percent of REM in total sleep in neonate versus healthy adult
neonate - 50% N3 - 25%
52
medication for hypertensive crisis from MAOIs and cocaine induced hypertension
phentolamine (alpha 1 blockade)
53
biggest risk factor for childhood abuse/neglect
low SES - financial stress
54
dissociative fugue
lasts min-months of sudden unexpected travel away from home with inability to recall one's past/identity (typically triggered by trauma) unaware
55
which mental disorder is predominantly women (10:1)
eating disorders
56
encopresis
repeated passage of feces into inappropriate places for >3 months linked to sexual trauma
57
pathological gamblers have what neurochemical abnormalities?
low plasma MHPG concentrations low platelet MAO concentrations --> serotonergic dysfunction --> impulse issues
58
for conduct disorder, symptoms have to be present before age
13
59
which analyst created concepts of archetypes, collective unconscious, introverts vs extroverts
Carl Jung
60
What is Eric Fromm known for?
creating five personality types
61
What concept is Kurt Goldstein known for?
Self-actualization
62
who proposed theories on an infant's experience of pleasure and its effect on infant-mother relationship
Edith Jacobson
63
benzos in pregnancy are which category
D
64
what is the most common reason for psychiatric malpractice suits?
suicide
65
respondeat superior in legalese
person occupying a high position in hierarchy is responsible for those in lower positions
66
kappa is studying what
number for binary data that tell us if something is reliable often measures degree of agreement between raters in a study
67
does libido decrease in women during pregnancy?
no - for many, it increases!
68
name of cognitive test where patient sees geometric figures for 10 sec and then asked to draw from memory
Benton visual retention test
69
anticipation defense mechanism
planning for future inner discomfort (mature)
70
which bipolar med associated with hyperparathyroidism
lithium
71
which med associated with eosinophilic colitis
clozapine
72
who came up with object relations theory
Melanie Klein
73
who used the term "epigenetic view of development?"
Erik Erikson
74
how long of worrying about future panic attack to meet criteria for panic disorder?
1 month
75
which recreational drug can cause severe hyperthermic syndrome that can progress to DIC, rhabdo, liver/kidney failure, death?
MDMA
76
for social anxiety, is combining CBT and SSRIs more effective than one alone?
no guess not
77
can nurses extend seclusion time if they feel patient is still agitated
no - only physician
78
Methadone is metabolized by CYP
3A4
79
what's biggest risk factor that would lead to IP over OP detox
history of DTs
80
cyclothymic disorder criteria
hypomanic episodes + depressive symptoms but dont meet criteria for major depression 2 years
81
if someone has hypomanic episodes and no depressive symptoms they meet criteria for
other specific bipolar and related disorder
82
what is the correct action when patient is on clozapine and ANC is 500-999
stop clozapine tried again when clozapine improves monitor ANC daily until it's over 1000
83
what is the correct action when patient is on clozapine and ANC is 1000-1499
switch to 3x/week monitoring until it's back above 1500
84
what is the correct action when patient is on clozapine and ANC is <500
stop clozapine only rechallenged after heme consult
85
psychological side effects of interferon
depression, SI, cognitive inefficiency