[6] Filariasis Flashcards Preview

[OS 217] Infectious Diseases > [6] Filariasis > Flashcards

Flashcards in [6] Filariasis Deck (17):
1

Under the ultrasound what sign can indicate a Filariasis infection

Dancing Sign

2

Drug of Choice for Filariasis

Diethylcarbamazine

(Albendazole is also used in combination for elimination programs)

3

Annual Mass Drug Administration for Filariasis

Diethylcarbamazine 6mg/kg
Albendazole 400mg

4

How many times must someone be bitten by an L3-Larvae carrying mosquito to contract Filariasis?

No definite number of times. The important part is the duration of exposure. This is because the degree of illness is proportional to the number of infective larvae inside and they do not multiply in humans.

5

How long does it take for a Filariatic larva to become an adult?

Approximately 1 year

6

What is Wolbachia?

Symbiotic endobacteria that infect filarial nematodes

7

Treatment against Wolbachia

Doxycycline for 4-8 weeks

8

Wuchureria brancrofti vectors found in breeds in water accumulated in the axils of abaca and banana plants

Aedes peocilus

9

Brugia malayi vectors that breed in freshwater swamps and rice fields

Mansonia spp.

10

Blood collection should be performed in this manner to coincide with the appearance of microfilariae

Peripheral blood collection at night

11

Infective Stage of Filariasis

L3 Larvae

12

Diagnostic Stage of Filariasis

Microfilariae

13

Adult Life Span of Filariasis

5-7 Years

14

How do we get an adult specimen of the worms?

Biopsy and/or lymphatic surgical procedures (UTZ-Guided)

15

Dominant cytokine response during initial infection of Filariasis

TH2 Cytokine Response: IL4, IL5, IL10

16

Dominant cytokine response during Inflammatory Phase infection of Filariasis

TH1 Cytokine Response: IFN-y

17

Treatment for Wolbachia Endoymbiont

Doxycycline for 4-8 weeks