Flashcards in  Filariasis Deck (17):
Under the ultrasound what sign can indicate a Filariasis infection
Drug of Choice for Filariasis
(Albendazole is also used in combination for elimination programs)
Annual Mass Drug Administration for Filariasis
How many times must someone be bitten by an L3-Larvae carrying mosquito to contract Filariasis?
No definite number of times. The important part is the duration of exposure. This is because the degree of illness is proportional to the number of infective larvae inside and they do not multiply in humans.
How long does it take for a Filariatic larva to become an adult?
Approximately 1 year
What is Wolbachia?
Symbiotic endobacteria that infect filarial nematodes
Treatment against Wolbachia
Doxycycline for 4-8 weeks
Wuchureria brancrofti vectors found in breeds in water accumulated in the axils of abaca and banana plants
Brugia malayi vectors that breed in freshwater swamps and rice fields
Blood collection should be performed in this manner to coincide with the appearance of microfilariae
Peripheral blood collection at night
Infective Stage of Filariasis
Diagnostic Stage of Filariasis
Adult Life Span of Filariasis
How do we get an adult specimen of the worms?
Biopsy and/or lymphatic surgical procedures (UTZ-Guided)
Dominant cytokine response during initial infection of Filariasis
TH2 Cytokine Response: IL4, IL5, IL10
Dominant cytokine response during Inflammatory Phase infection of Filariasis
TH1 Cytokine Response: IFN-y