3) Structure/Function of Cells in Nervous System Flashcards

1
Q

What are all the key part of a neuron

A

axon, myelinated sheath, soma (cell body, dendrites, terminal buttons)

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2
Q

What 3 types of neurons can you get?

A

Sensory- detects external/internal changes (CNS, PNS, light, sound)
Motor neuron- controls muscle contraction, gland secretion (CNS, PNS)
Interneurons- Found ONLY in the CNS, involved in cognition

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3
Q

The structure of a neuron can be divide into which 3 types

A

Multipolar neuron- 1 axon, many dendrites attached to soma
Bipolar neuron- 1 axon, 1 dendrite attached to soma
Unipolar neuron- 1 axon attached to soma, on ebranch received sensory info, other sends info TO CNS

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4
Q

What are the 2 key supporting GLIAL cells in the CNS/ Blood-Brain Barrier (BBB) called & their function?

A

Oligodendrocytes- forms myelin sheath, insulation, lipids
Astrocytes (star cells)- provide physical support to neurons, CNS, nourishment, clean up dead neuron debris, form scar tissue, helps form the BBB

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5
Q

What is the BBB

A

Semi-permeable barrier separating blood from the circulatory system and CSF in the brain. Prevents blood entering the brain and keeps it safe

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6
Q

What’s the region in the medulla called, where the BBB is weak + what does it allow to enter?

A

It’s called the Area Postremema. Allows toxins to get in/stimulate the area = body wants to expel the poison from body&raquo_space; this initiates vomiting

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7
Q

Explain the withdrawal reflex process

A

1) Dendrite detects pain
2) Pains follows up axon
3) muscle withdraws from pain
4) Interneuron in spinal cord excites motor neuron to cause muscle contraction

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8
Q

How does the role of inhibition alter the withdrawal reflex

A

Follows the same first few steps. But before muscle contraction occurs, another inter neuron inhibits a motor neuron, preventing muscular contraction. (if the person can withstand the heat of a pot for example)

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9
Q

What is a synapse

A

Location for communication between separate neurons. It is the junction between them (terminal button of one and soma of another)

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10
Q

Why is there a synaptic gap between the 2 neurons

A

Action Potentials can’t cross the cleft, therefore nerve impulses are carried by neurotransmitter chemicals

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11
Q

Which neuron sends/receives impulses

A

Pre-synaptic- sends the impulse

Post-synaptic- receives the impulse

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12
Q

Where are neurotransmitter chemicals made and stored?

A

Made in the pre-synaptic neuron and stored in synpatic vesicles.

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13
Q

How does a post-synaptic neuron receive the neurotransmitter chemical?

A

It’s membrane has chemical-gated ion channels called neuroreceptors, with specific binding sites for certain neurochems (fitting the binding site like a lock and key)

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14
Q

Explain what an ionotropic receptor of an ion channel allows for

A

Direct opening of the ion channel on it’s actual binding site

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15
Q

Explain what an indirect opening of an ion channel is

A

Occurs at a metabotropic receptor, where a transmitter molecule binds to a receptor, which activates an adjacent protein to break away and bind with the ion channel of interest to open it and allows ions through the cell.
(Remember the door bell analogy- you hear it, but someone else opens the door)

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16
Q

Explain reuptake and why it is necessary

A

Reuptake is the leftover molecules of neurotrans in the cleft that weren’t used in the nerve impulse , get returned back into the terminal buttons of the pre-synaptic neuron

17
Q

Explain what an EPSP is

A

Excitatory Post Synaptic Potential-
causes an excitatory depolarisation of the postsynaptic neuron, meaning the nerve impulse is able to continue into the next neuron (threshold is met)

18
Q

Explain what an IPSP is

A

Inhibitory Post Synaptic Potential-
counteracts EPSPs on other side of postsynaptic neuron, so APs not triggered in axon for nerve impulse to continue onto next neuron

19
Q

Describe the nature of the 3 main ion channels and whether they are EPSP or IPSP

A

Sodium (Na+) = EPSP, influx into cleft causes depolarisation
Potassium (K+)= IPSP (efflux out of cleft causes hyperpolarisation)
Chlorine (Cl-) = IPSP (influx causes hyperpolarisation)

20
Q

Explain what neuronal integration is

A

Process of inhibitory and excitatory PSPs summating and controlling the firing rate of a neuron

21
Q

What happens if there are ONLY EPSPs present and what happens when more IPSPs are introduced

A

If just EPSPs the excitatory threshold at the axon hillock is met and a neuron fires.
If more IPSPs are present, it is more likely that APs won’t be triggered and the neuron won’t fire

22
Q

EPSPs always cause what…

IPSPs always cause what…

A

1) Depolarisation

2) Hyperpolarisation