55. Cells of the immune system. T and B cell populations, markers. Cell cooperation.

Question 1

Immune cells are classified into myeloid and lymphoid cells. The myeloid group is the class of the granulocytes and monocytes. Some granulocytes are neutrophils, basophils and eosinophils. Monocyte derivatives are macrophages, Kupffer cells and dendritic cells. In the class of the lymphoid cells are the T-cells the B-cells and the NK cells.

Answer 1

Immune cells are classified into myeloid and lymphoid cells. The myeloid group is the class of the granulocytes and monocytes. Some granulocytes are neutrophils, basophils and eosinophils. Monocyte derivatives are macrophages, Kupffer cells and dendritic cells. In the class of the lymphoid cells are the T-cells the B-cells and the NK cells.

Question 2

T cell derivatives - cytotoxic cells and T helper cells

B cell derivatives - plasma cell

Answer 2

T cell derivatives - cytotoxic cells and T helper cells

B cell derivatives - plasma cell

Question 3

Immune cells originate from a stem cell - either differentiates into lymphoid or myeloid progenitor cell - which further differentiate into their derivatives - T or B cells. Development from the stem cell takes place in the bone marrow + finishes there except for granulocytes, mast cells and macrophages which settle in the tissues.

Natural killer cells, kill cells that are infected with the virus - e.g. an eosinophil

Answer 3

Immune cells originate from a stem cell - either differentiates into lymphoid or myeloid progenitor cell - which further differentiate into their derivatives - T or B cells. Development from the stem cell takes place in the bone marrow + finishes there except for granulocytes, mast cells and macrophages which settle in the tissues.

Natural killer cells, kill cells that are infected with the virus - e.g. an eosinophil

Question 4

Mast cells play a role in the immunity against parasites

Cells of the adaptive immune response: T and B cells

B cells are antibody producing plasma cells while T-cells are cytotoxic.

T + B cells have a receptor which is unique for a specific antigenic determent.

Answer 4

Mast cells play a role in the immunity against parasites

Cells of the adaptive immune response: T and B cells

B cells are antibody producing plasma cells while T-cells are cytotoxic.

T + B cells have a receptor which is unique for a specific antigenic determent.

Question 5

Immune cells interact in 2 ways

1. direct contact between the cells
2. cytosine signalling (acting in auto/ paracrine fashion)

Answer 5

Immune cells interact in 2 ways

1. direct contact between the cells
2. cytosine signalling (acting in auto/ paracrine fashion)

Question 6

The central role of the Th (T helper cells) cells is the proliferation of effector cells and to enhance the functional activities of other cells.

Memory B and T cells are created during the primary response. B cells have an high affinity Ig receptor - they can take up the antigen at a lower concentration than other antigen presenting cells that lack FGR

Answer 6

The central role of the Th (T helper cells) cells is the proliferation of effector cells and to enhance the functional activities of other cells.

Memory B and T cells are created during the primary response. B cells have an high affinity Ig receptor - they can take up the antigen at a lower concentration than other antigen presenting cells that lack FGR