STI 1

Question 1

acute anterior utheritis with painful urinationm and urerthral discharge.

Answer 1

gonorrhea

Question 2

vaginal discharge, dysuria, bleeding

Answer 2

gonorrhea

Question 3

anal discharge and bleeding

Answer 3

anal gonorrhea

Question 4

morphology of N gonorrhoeae

Answer 4

gram negative diplococci resembling a kidney bean

Question 5

presumptive diagnosis of N gonorrhoeae

Answer 5

gram - (good enough for guys) and colonies turn black on oxidative reagent (needed for females)

Question 6

virulence factors of N gonorrhoeae

Answer 6

protein I/Opa protein
LOS
antigenic variation
ohase shift
IgA protease

Question 7

N gonorrhoeae virulence factor respinsible for most symptoms

Answer 7

LOS

Question 8

pustular skin lesions, septic arthritis,

Answer 8

disseminated gonococcal infection

Question 9

treatment of neisseria newborn eyes

Answer 9

profylaxis antibiotics

Question 10

potential complication of N gonorrhoeae in women

Answer 10

PID—> endometritis/salphinitis/peritonitis –> tubal obstruction/ectopic pregnancy

Question 11

stain for chlamydia

Answer 11

giemsa stain

Question 12

outer membrane structures NOT in chlamydia

Answer 12

peptidiglycan or muramic acid

Question 13

stage chlymadia is taken up by the cell

Answer 13

infectious stage/elementary body

Question 14

group of chlamydia within a vacoule

Answer 14

inclusion body

Question 15

major cause of preventable blindness in the world

Answer 15

C trachomatis

Question 16

pathenogenisis of trachoma

Answer 16

chronic and repeated infection results in scarring of conjunctiva

scar tissue from the delayed hypersensitivity response causes distortion of eyelids so that eyelashes abrade cornea

inflammation of cornea neovascularization scars cornea (pannus) resulting in permanant blindness

Question 17

vector of trachoma

Answer 17

flies

Question 18

self liminting trachoma conjunctives

Answer 18

inclusion conjunctivitis

Question 19

trachoma type common in US

Answer 19

inclusion conjunctivitis

Question 20

most common STI in US

Answer 20

genital chlamydia

Question 21

pathogenisis of genital chlamydia

Answer 21

orginisms bind to toll receptors which elicit translocation of NFkB in host cell. This effects production of IL-1 and IL-8.

Question 22

causes the damage of genital chlamydia

Answer 22

acute inflamatory response of PMN in epithelium and mononuclear cells in submucosa

Question 23

most cases are asymptomatic

Answer 23

genital chlamydia

Question 24

causes reiter’s disease

Answer 24

genital chlamydia

Question 25

diagnosis of genital chlamydia

Answer 25

ampflication of DNA or RNA

Question 26

what must be gotten to culture genital chlamydia

Answer 26

cells from urethra or cervix

Question 27

most common neonate genital chlamydia infection

Answer 27

inclusion conjunctivitis

Question 28

diagnosis of neonate chylmidia conjunctivitis

Answer 28

culture or giesma stain

Question 29

diagnosis of chymida pneumonitis

Answer 29

high titer of IgM atnibody

Question 30

chlymidia infection in homosexuals

Answer 30

lymphogranuloma venerum

Question 31

shallow ulcer or papule on genitalis

Answer 31

lymphogranuloma venerum

Question 32

can cause rectal strictures of elephantitis

Answer 32

lymphogranuloma venerum