Old Exam I Flashcards

1
Q

Dendrotoxin

A

Blocks VR K channels

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2
Q

Dystrophin

A

DMD - muscular dystrophy

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3
Q

Phospolipase A2 aactivation

A

Ultimately leads to leukotriene production

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4
Q

DHP receptors are

A

Present in the sarcolemma

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5
Q

When relaxed, a sarcomere’s band

A

Gets wider

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6
Q

Neostigmine

A

Inhibits ACHase, Counteracts effects of curare (and anesthesia!)

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7
Q

Hyperpolarization is due to

A

Efflux of K

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8
Q

APs involve ____ channels, GPs involve ____ channels

A

Voltage gated, chemical gated

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9
Q

T/F, skeletal muscles have gap junctions?

A

False! This is smooth muscle.

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10
Q

Neural temporal summation is when

A

neuron releases lots of neural transmitters at a time (frequency increases!)

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11
Q

IP3 does what?

A

Causes Ca to be released from ER

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12
Q

Threshold potential is determined by

A

The voltage that VR Na channels open

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13
Q

Absolute refractory period is when what are inactivated?

A

VR Na channels

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14
Q

A sub threshold stimulus delivered to a neuron

A

Results in a graded potential, causes chemically regulated channels to open, but not voltage regulated

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15
Q

Muscle fibers are a collection of

A

myofibrils

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16
Q

Myofibrils are a collection of

A

Actin and myosin

17
Q

Muscle fascicles are a collection of

A

Muscle cells

18
Q

Oxygen debt refers to

A

Reclaiming ATP from excess lactic acid

19
Q

Oxygen debt refers to

A

Reclaiming ATP from excess lactic acid

20
Q

Smooth muscle cells contract by

A

Having Ca - calmodulin complex activated by MYOSIN KINASE cascade

21
Q

Myoglobin

A

Allows muscle fibers to remain aerobic even when blood cannot bring O2

22
Q

Latency in a twitch is due to the time it takes

A

An AP to be generated and travel along sarcolemma, VR Ca channels located in T-tubule to open

23
Q

(Graph in which stimulus increases with frequency)

A

Recruitment

24
Q

Curare

A

CR Channel blocker

25
Q

Flexeril

A

CNS

26
Q

Tetrodotoxin

A

VR Na channel blocker