glucose 6 phosphate dehydrogenase deficiency

Question 1

what type of inheritance disorder?

Answer 1

x linked recessive

Question 2

common in what populations?

Answer 2

African American and mediterannean

Question 3

when does G6PD activity decline?

Answer 3

as RBC age beyond 40 days, oxidative drugs and infection (malaria) cause episodic hemolysis

Question 4

what are oxidant drugs that can cause hemolysis?

Answer 4

fava bean consumption
anti malarial drugs
sulfa drugs
aspirin

Question 5

severe glucose 6 phosphate dehydrogenase deficiency may cause ___.

Answer 5

chronic hemolysis

Question 6

is there splenomegaly present in glucose 6 phosphate dehydrogenase deficiency

Answer 6

no

Question 7

symptoms of glucose 6 phosphate dehydrogenase deficiency

Answer 7

jaundice, dark urine, abdominal and lower back pain

Question 8

treatment for glucose 6 phosphate dehydrogenase deficiency

Answer 8

usually self limited, avoid triggers

Question 9

what will land show for glucose 6 phosphate dehydrogenase deficiency

Answer 9

normocytic, normochromic, elevated relic counts and indirect bilirubin during hemolytic episodes

Question 10

what will peripheral smear show in glucose 6 phosphate dehydrogenase deficiency

Answer 10

Heinz bodies and bite cells